暴露于环境镉中的人群肝脏和肾脏中硒、锌、铜及镉的浓度

Selenium, zinc, copper and cadmium concentration in livers and kidneys of people exposed to environmental cadmium.

作者信息

Kido T, Tsuritani I, Honda R, Yamaya H, Ishizaki M, Yamada Y, Nogawa K

机构信息

Department of Hygiene, Kanazawa Medical University, Ishikawa, Japan.

出版信息

J Trace Elem Electrolytes Health Dis. 1988 Jun;2(2):101-4.

PMID:2980796

Abstract

Selenium (Se), Cadmium (Cd), Zinc (Zn) and Copper (Cu) concentrations have been determined in the kidney cortex, medulla and liver of 21 Cd-exposed and 15 nonexposed autopsied subjects. In the kidney cortex, all four metals were significantly lower in the Cd-exposed subjects than in the nonexposed ones. In the liver Se levels were almost the same in both groups. Significant correlation coefficients between Se and the three metals were found in the kidney cortex of all the subjects. In the liver significant correlation coefficients were only seen between Se and Cu in the Cd-exposed subjects. These results indicated that the distribution of Se in humans chronically exposed to environmental Cd is different from that in humans exposed to environmental organic mercury.

摘要

已测定了21名镉暴露尸检对象和15名未暴露尸检对象的肾皮质、髓质及肝脏中硒（Se）、镉（Cd）、锌（Zn）和铜（Cu）的浓度。在肾皮质中，镉暴露对象的所有四种金属含量均显著低于未暴露对象。两组肝脏中的硒水平几乎相同。在所有对象的肾皮质中，硒与其他三种金属之间存在显著的相关系数。在肝脏中，仅在镉暴露对象中发现硒与铜之间存在显著的相关系数。这些结果表明，长期暴露于环境镉的人群中硒的分布与暴露于环境有机汞的人群不同。