MC1R 基因中的非同义单核苷酸多态性与家鸭（Anas platyrhynchos）的黑色扩展变体有关。
Non-synonymous SNPs in MC1R gene are associated with the extended black variant in domestic ducks (Anas platyrhynchos).
机构信息
Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, P.R. China.
出版信息
Anim Genet. 2013 Apr;44(2):214-6. doi: 10.1111/j.1365-2052.2012.02377.x. Epub 2012 May 17.
In this study, we performed a sequence characterization of the duck melanocortin 1 receptor (alpha-melanocyte stimulating hormone receptor) (MC1R) gene to analyze the relationship between MC1R polymorphism and the extended black variant in domestic ducks based on the extended black (E) and non-extended black (e(+) ) allele hypothesis of the duck MC1R gene. Both c.52G>A and c.376G>A substitutions are highly associated with the duck extended black variant (P < 0.01), but the novel c.52G>A substitution is more of a fit for the allele hypothesis of the duck MC1R gene.
在这项研究中，我们对鸭黑色素皮质素 1 受体（α-促黑素细胞激素受体）（MC1R）基因进行了序列特征分析，基于鸭 MC1R 基因的扩展黑（E）和非扩展黑（e(+)）等位基因假说，分析了 MC1R 多态性与家鸭扩展黑变体之间的关系。c.52G>A 和 c.376G>A 取代均与鸭扩展黑变体高度相关（P<0.01），但新型 c.52G>A 取代更符合鸭 MC1R 基因的等位基因假说。
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