Korovina N A, Gavriushova L P, Ametov A S, Tvorogova T M, Mumladze E B, Toritsina L K
Pediatriia. 1990(9):23-7.
A total of 28 children with different varieties of glomerulonephritis were examined for the pituitary-gonadal system (PGS). The examination included measurements of follicle-stimulating and luteinizing hormones, prolactin, estradiol, progesterone and testosterone. To define standards of the content of the hormones under study, 45 children of the control group were examined. The relationship was analyzed between the content of hormones and the disease activity and gravity. The most active phase of glomerulonephritis was characterized by maximal alterations in the content of pituitary and gonadal hormones. The content of the latter ones appeared to be considerably changed in patients with the mixed pattern of glomerulonephritis, attesting to profound functional derangements in the PGS. The intensity of those derangements was determined by the severity of the pathological process.
对总共28名患有不同类型肾小球肾炎的儿童进行了垂体-性腺系统（PGS）检查。检查内容包括测量促卵泡激素、促黄体生成素、催乳素、雌二醇、孕酮和睾酮。为确定所研究激素的含量标准，对45名对照组儿童进行了检查。分析了激素含量与疾病活动度和严重程度之间的关系。肾小球肾炎最活跃阶段的特点是垂体和性腺激素含量发生最大变化。在肾小球肾炎混合型患者中，后者的含量似乎有相当大的变化，证明PGS存在严重的功能紊乱。这些紊乱的强度取决于病理过程的严重程度。
