UMR-CNRS 7295 "Centre de Recherches sur la Cognition et l'Apprentissage," Université de Poitiers, Poitiers, France.
Alzheimer Dis Assoc Disord. 2013 Apr-Jun;27(2):116-22. doi: 10.1097/WAD.0b013e318257dc31.
Episodic memory deficits are predominately the first cognitive impairment in Alzheimer disease (AD). Previous studies have demonstrated that these deficits are specifically linked to autonoetic consciousness impairment, whereas noetic consciousness remains preserved in AD. This study focused on the self-reference effect and examined emotional valence, as it has been shown that emotional content can enhance memory in AD. A task involving recognition of emotional versus neutral adjective traits after self-reference versus semantic encoding, and using the Remember/Know/Guess paradigm was administered to 22 AD patients and 18 normal controls. Results for AD patients show that self-reference increased autonoetic consciousness only for emotional and particularly negative trait adjectives. This interesting result indicates that neutral valence does not allow properties of the self to emerge in AD patients because of the progressive loss of the sense of self-linked to the disease, whereas emotional valence does.
情景记忆缺陷是阿尔茨海默病（AD）患者最早出现的认知障碍之一。先前的研究表明，这些缺陷与自主意识损伤密切相关，而在 AD 患者中，认知意识仍然存在。本研究专注于自我参照效应，并研究了情绪效价，因为已经表明情绪内容可以增强 AD 患者的记忆。一项任务涉及在自我参照与语义编码后识别情绪与中性形容词特征，并使用“记得/知道/猜测”范式，对 22 名 AD 患者和 18 名正常对照者进行了测试。AD 患者的结果表明，自我参照仅增加了情绪形容词，尤其是负性形容词的自主意识。这一有趣的结果表明，由于与疾病相关的自我感逐渐丧失，中性效价不能使自我的属性在 AD 患者中显现出来，而情绪效价则可以。
