Department of Ophthalmology, College of Medicine, Soonchunhyang University, Seoul, Korea.
Retina. 2012 Oct;32(9):1743-8. doi: 10.1097/IAE.0b013e3182551c3c.
To determine long-term surgical findings and outcomes after vitrectomy for symptomatic lamellar macular holes.
This is a retrospective, consecutive, interventional case series. Sixteen patients (31 eyes) with lamellar macular holes and central visual loss participated in the study. All patients underwent 3-port pars plana vitrectomy with membranectomy and/or internal limiting membrane peeling and gas tamponade under the care of one author. Best-corrected visual acuity and optical coherence tomography appearance were determined preoperatively and postoperatively.
Final visual acuity improved more than 2 lines postoperatively in 18 eyes (58.1%) and decreased in 2 eyes (6.5%) leading to a mean gain of 0.18 logarithm of the minimum angle of resolution visual acuity during the mean follow-up period of 39 ± 24 months (12-85 months). Twenty-eight eyes (90.3%) improved or normalized in foveal appearance on postoperative optical coherence tomography images of the macula, 1 eye remained unchanged, and 1 eye (3.2%) had chronic cystoid macular edema, 1 eye was unchanged, and 1 eye showed recurrence of lamellar macular hole.
In patients with central visual loss from lamellar macular holes, vitrectomy, membranectomy, and/or internal limiting membrane peeling and gas tamponade appear to have a beneficial effect for a mean of 3 years.
确定玻璃体切除术后症状性板层黄斑裂孔的长期手术结果。
这是一项回顾性、连续的、干预性病例系列研究。16 名（31 只眼）板层黄斑裂孔伴中心视力丧失的患者参与了本研究。所有患者均由一位作者行 3 端口经睫状体平坦部玻璃体切除术，行膜切除术和/或内界膜剥除术，并在气液交换下进行眼内填充。在术前和术后分别测定最佳矫正视力和光学相干断层扫描（OCT）的表现。
术后 18 只眼（58.1%）视力提高超过 2 行，2 只眼（6.5%）视力下降，平均随访 39±24 个月（12-85 个月）后平均对数最小分辨角视力提高 0.18。28 只眼（90.3%）术后黄斑 OCT 图像上的黄斑中心凹外观改善或正常，1 只眼保持不变，1 只眼（3.2%）出现慢性囊样黄斑水肿，1 只眼保持不变，1 只眼出现板层黄斑裂孔复发。
对于中心视力丧失的板层黄斑裂孔患者，玻璃体切除术、膜切除术和/或内界膜剥除术联合气液交换填充似乎在平均 3 年内具有有益的效果。
