长期观察期内根据频域光学相干断层扫描检查结果分析板层黄斑裂孔的形态学变化

Morphological Changes in Lamellar Macular Holes According to SD-OCT Examination over a Long Observation Period.

作者信息

Kal Magdalena, Chojnowska-Ćwiąkała Izabela, Winiarczyk Mateusz, Jasielska Monika, Mackiewicz Jerzy

机构信息

Collegium Medicum of Jan Kochanowski University in Kielce, Ophthalmic Clinic of the Voivodeship Hospital in Kielce, 25-369 Kielce, Poland.

Institute of Medical Science of Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.

出版信息

Diagnostics (Basel). 2021 Jun 23;11(7):1145. doi: 10.3390/diagnostics11071145.

DOI:10.3390/diagnostics11071145

PMID:34201679

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8305568/

Abstract

BACKGROUND

The aim of this study was to evaluate the quantitative morphological changes in lamellar macular holes (LMHs) based on SD-OCT examinations and to assess the correlations among minimal retinal thickness (MRT), reading vision (RV), and best corrected visual acuity (BCVA) over a 36-month follow-up period.

METHODS

A group of 40 patients (44 eyes) with LMH was evaluated, with an average age of 69.87 (SD = 10.14). The quantitative parameters monitored in the follow-up period (at 0, 3, 6, 12, 18, 24, 30, and 36 months) were tested for normality of distribution by Shapiro-Wilk and Kolmogorov-Smirnov tests.

RESULTS

The RV and BCVA values were stable, and no significant changes were found at any of the check-ups during the 36-month follow-up period (BCVA = 0.435 and RV = 0.0999). The analysis of individual quantitative LMH parameters during the 36-month follow-up period did not demonstrate statistically significant differences: MRT ( = 0.461), Max RT temporal ( = 0.051), Max RT nasal ( = 0.364), inner diameter (ID) ( = 0.089), and outer diameter (OD) ( = 0.985).

CONCLUSIONS

The observations at 0, 6, 12, 18, 24, 30, and 36 months revealed moderate and significant correlations between RV and MRT. No significant correlation between BCVA and MRT was observed.

摘要

背景

本研究旨在基于频域光学相干断层扫描（SD - OCT）检查评估板层黄斑裂孔（LMH）的定量形态学变化，并在36个月的随访期内评估最小视网膜厚度（MRT）、阅读视力（RV）和最佳矫正视力（BCVA）之间的相关性。

方法

对一组40例（44只眼）LMH患者进行评估，平均年龄为69.87岁（标准差 = 10.14）。通过Shapiro - Wilk和Kolmogorov - Smirnov检验对随访期（0、3、6、12、18、24、30和36个月）监测的定量参数进行分布正态性检验。

结果

RV和BCVA值稳定，在36个月随访期内的任何一次检查中均未发现显著变化（BCVA = 0.435，RV = 0.0999）。对36个月随访期内LMH个体定量参数的分析未显示出统计学上的显著差异：MRT（ = 0.461）、颞侧最大视网膜厚度（ = 0.051）、鼻侧最大视网膜厚度（ = 0.364）、内径（ID）（ = 0.089）和外径（OD）（ = 0.985）。