• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人类基因和基因诊断方法专利的命运和未来。

The fate and future of patents on human genes and genetic diagnostic methods.

机构信息

Faculty of Pharmaceutical Sciences and Centre for Intellectual Property Rights, University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.

出版信息

Nat Rev Genet. 2012 May 18;13(6):441-8. doi: 10.1038/nrg3255.

DOI:10.1038/nrg3255
PMID:22596320
Abstract

Since the 1970s, patents on human genes and genetic diagnostic methods have been granted under the assumption that they stimulate the development of diagnostic methods and therapeutic products. However, the principles and practices of patenting vary between jurisdictions. Do patent holders, researchers, clinicians and patients really benefit from this heterogeneous patent system? We discuss the problems that result from the current system and suggest how they might be solved by altering the way in which patents are granted and/or licensed.

摘要

自 20 世纪 70 年代以来,授予了人类基因和基因诊断方法的专利,前提是它们可以促进诊断方法和治疗产品的开发。然而,专利授予的原则和实践在不同司法管辖区有所不同。专利持有人、研究人员、临床医生和患者是否真的从这个异质的专利系统中受益?我们讨论了当前系统所产生的问题,并提出了通过改变专利授予和/或许可的方式来解决这些问题的建议。

相似文献

1
The fate and future of patents on human genes and genetic diagnostic methods.人类基因和基因诊断方法专利的命运和未来。
Nat Rev Genet. 2012 May 18;13(6):441-8. doi: 10.1038/nrg3255.
2
Fortune and hindsight: gene patents' muted effect on medical practice.时运与后见之明:基因专利对医疗实践的影响微乎其微。
Br Med Bull. 2018 Jun 1;126(1):37-45. doi: 10.1093/bmb/ldy009.
3
Patenting and licensing in genetic testing: recommendations of the European Society of Human Genetics.基因检测中的专利与许可:欧洲人类遗传学学会的建议
Eur J Hum Genet. 2008 May;16 Suppl 1:S10-9. doi: 10.1038/ejhg.2008.37.
4
Patenting and licensing in genetic testing: ethical, legal, and social issues.基因检测中的专利与许可:伦理、法律及社会问题
Eur J Hum Genet. 2008 May;16 Suppl 1:S10-50.
5
Patenting Foundational Technologies: Lessons From CRISPR and Other Core Biotechnologies.专利基础技术:来自 CRISPR 和其他核心生物技术的经验教训。
Am J Bioeth. 2018 Dec;18(12):36-48. doi: 10.1080/15265161.2018.1531160.
6
Introduction.引言。
Eur J Hum Genet. 2008 May;16 Suppl 1:S1-2. doi: 10.1038/ejhg.2008.35.
7
Patent or perish? An ethical approach to patenting human genes and proteins.
Pharmacogenomics J. 2002;2(6):361-6. doi: 10.1038/sj.tpj.6500140.
8
Take off your genes and let the doctor have a look: why the Mayo and Myriad decisions have invalidated method claims for genetic diagnostic testing.剖析你的基因,让医生来看看:为何梅奥诊所和麦利亚德公司的裁决使基因诊断测试的方法专利无效。
Am Univ Law Rev. 2013;63(1):173-217.
9
Diagnostic method patents and harms to follow-on innovation.诊断方法专利与后续创新的危害。
Harv Law Rev. 2013 Mar;126(5):1370-91.
10
Listening behind the questions--how experts can improve the public discourse on gene patenting.
Pharmacogenomics. 2003 Jul;4(4):507-8. doi: 10.1517/phgs.4.4.507.22757.

引用本文的文献

1
Absolute and Relative Quantification of Multiplex DNA Assays Based on an Elemental Labeling Strategy.基于元素标记策略的多重DNA分析的绝对定量和相对定量
Angew Chem Weinheim Bergstr Ger. 2013 Jan 28;125(5):1506-1511. doi: 10.1002/ange.201206903. Epub 2012 Dec 13.
2
Continental drift? Do European clinical genetic testing laboratories have a patent problem?大陆漂移?欧洲临床遗传检测实验室有专利问题吗?
Eur J Hum Genet. 2019 Jul;27(7):997-1007. doi: 10.1038/s41431-019-0368-7. Epub 2019 Mar 7.
3
After Myriad, what makes a gene patent claim 'markedly different' from nature?

本文引用的文献

1
Intellectual property rights and innovation: Evidence from the human genome.知识产权与创新:来自人类基因组的证据。
J Polit Econ. 2010 Jul 1;121(1):1-27. doi: 10.1086/669706.
2
Debunking the myth that whole-genome sequencing infringes thousands of gene patents.揭穿全基因组测序侵犯数千项基因专利这一谬论。
Nat Biotechnol. 2012 Mar 7;30(3):240-4. doi: 10.1038/nbt.2146.
3
Genomics, health care, and society.基因组学、医疗保健与社会。
在Myriad案之后,是什么使得一项基因专利权利要求与自然“明显不同”?
Nat Biotechnol. 2017 Sep 11;35(9):820-825. doi: 10.1038/nbt.3953.
4
Gene patents still alive and kicking: their impact on provision of genetic testing for long QT syndrome in the Canadian public health-care system.基因专利仍然存在并具有影响力:它们对加拿大公共医疗保健系统中长 QT 综合征基因检测的提供的影响。
Genet Med. 2017 Nov;19(11):1253-1259. doi: 10.1038/gim.2017.43. Epub 2017 May 11.
5
Eteplirsen in the treatment of Duchenne muscular dystrophy.依特普肽治疗杜氏肌营养不良症
Drug Des Devel Ther. 2017 Feb 28;11:533-545. doi: 10.2147/DDDT.S97635. eCollection 2017.
6
Ethics education for clinician-researchers in genetics: The combined approach.面向基因领域临床研究人员的伦理教育:综合方法
Appl Transl Genom. 2014 Dec 16;4:16-20. doi: 10.1016/j.atg.2014.12.001. eCollection 2015 Mar.
7
Are the gene-patent storm clouds dissipating? A global snapshot.基因专利的阴云正在消散吗?全球快照。
Nat Biotechnol. 2015 Apr;33(4):347-52. doi: 10.1038/nbt.3182.
8
Do recent US Supreme Court rulings on patenting of genes and genetic diagnostics affect the practice of genetic screening and diagnosis in prenatal and reproductive care?美国最高法院最近关于基因及基因诊断专利的裁决是否会影响产前和生殖保健中基因筛查与诊断的实践?
Prenat Diagn. 2014 Oct;34(10):921-6. doi: 10.1002/pd.4445. Epub 2014 Jul 31.
9
Looking back and moving forward: an historical perspective from laboratory genetic counselors.回顾与展望:实验室遗传咨询师的历史视角
J Genet Couns. 2014 Jun;23(3):363-70. doi: 10.1007/s10897-013-9670-7. Epub 2013 Nov 12.
10
The European BRCA patent oppositions and appeals: coloring inside the lines.欧洲BRCA专利异议与上诉:依规行事。
Nat Biotechnol. 2013 Aug;31(8):704-10. doi: 10.1038/nbt.2644.
N Engl J Med. 2011 Sep 15;365(11):1033-41. doi: 10.1056/NEJMra1010517.
4
Human DNA patent renewals on the decline.
Nat Biotechnol. 2011 Aug 5;29(8):711-3. doi: 10.1038/nbt.1930.
5
Intellectual property. Turning patent swords into shares.知识产权。将专利之剑转化为股份。
Science. 2010 Dec 17;330(6011):1630-1. doi: 10.1126/science.1189592.
6
The impact of human gene patents on genetic testing in the United Kingdom.人类基因专利对英国基因检测的影响。
Genet Med. 2011 Apr;13(4):320-4. doi: 10.1097/GIM.0b013e3181fc50bc.
7
Patently unpatentable: implications of the Myriad court decision on genetic diagnostics.明显不可专利:Myriad 法院判决对基因诊断学的影响。
Trends Biotechnol. 2010 Nov;28(11):548-51. doi: 10.1016/j.tibtech.2010.08.005.
8
DNA patents and diagnostics: not a pretty picture.DNA专利与诊断:情况不妙。
Nat Biotechnol. 2010 Aug;28(8):784-91. doi: 10.1038/nbt0810-784.
9
Patents in genomics and human genetics.基因组学和人类遗传学专利。
Annu Rev Genomics Hum Genet. 2010;11:383-425. doi: 10.1146/annurev-genom-082509-141811.
10
Legal uncertainty in the area of genetic diagnostic testing.遗传诊断检测领域的法律不确定性。
Nat Biotechnol. 2009 Oct;27(10):903-9. doi: 10.1038/nbt1009-903.