Chan H L
Division of Dermatology, National University Hospital, Singapore.
Singapore Med J. 1990 Oct;31(5):480-5.
Many general signs familiar to physicians can be found on the skin in cardiac patients. These include (a) cyanosis, central and peripheral, (b) erythremia, flushing and erythema, (c) digital clubbing and (d) alteration in texture. Specific cardiac conditions often have useful diagnostic cutaneous clues. Of these the association of coronary heart disease, hyperlipidemia and xanthomas is the most important. Rare syndromes such as the "leopard syndrome" often have distinctive skin signs. Multisystemic disorders may affect the heart and skin simultaneously or in sequence. They include collagen vascular diseases, amyloidosis, sarcoidosis and relapsing polychondritis. Finally iatrogenic disease arising from treatment of cardiac or cutaneous disease may induce changes in one or the other organ. The heart and the skin have much in common. These manifestations help elucidate the cause, evaluate the diagnosis, and follow the treatment and progress of these diseases.
心脏病患者的皮肤上可以发现许多医生熟悉的一般体征。这些体征包括：(a) 中央性和外周性发绀；(b) 红细胞增多、潮红和红斑；(c) 杵状指；(d) 质地改变。特定的心脏疾病通常有有用的诊断性皮肤线索。其中，冠心病、高脂血症和黄瘤的关联最为重要。罕见综合征如“豹皮综合征”通常有独特的皮肤体征。多系统疾病可能同时或相继影响心脏和皮肤。这些疾病包括胶原血管病、淀粉样变性、结节病和复发性多软骨炎。最后，因心脏或皮肤疾病治疗引起的医源性疾病可能会在一个或另一个器官中诱发变化。心脏和皮肤有许多共同之处。这些表现有助于阐明病因、评估诊断以及跟踪这些疾病的治疗和进展情况。
