Owen J H, Naito M, Bridwell K H, Oakley D M
Division of Orthopedic Surgery, Washington University School of Medicine, St. Louis, Missouri.
Spine (Phila Pa 1976). 1990 Sep;15(9):846-51. doi: 10.1097/00007632-199009000-00002.
Stagnara wake-up tests, blood flow measures, somatosensory evoked potentials (SEPs), and neurogenic-motor evoked potentials (NMEPs) were elicited from 20 hogs before and after spinal cord overdistraction at L3-L4. Overdistraction was maintained from 5 to 30 minutes after loss of NMEPs. Results suggest that the longer the duration of overdistraction the greater the likelihood of paraplegia. Blood flow measures indicated that reduced perfusion was greatest at the distraction site but extended proximally and distally. Finally, NMEPs were more sensitive to onset of overdistraction and a more valid indicator of paraplegia than SEPs. NMEPs should provide the surgeon with more time for initiation of intervention techniques than SEPs. Because NMEPs and SEPs provide information regarding different spinal cord tracts, the authors continue to use both methods for monitoring the functional integrity of the human spinal cord during corrective spine surgery.
在L3 - L4脊髓过度牵张前后，对20头猪进行了斯塔尼亚拉唤醒试验、血流测量、体感诱发电位（SEP）和神经源性运动诱发电位（NMEP）检测。在NMEP消失后，过度牵张持续5至30分钟。结果表明，过度牵张的持续时间越长，截瘫的可能性就越大。血流测量表明，灌注减少在牵张部位最为明显，但向近端和远端延伸。最后，NMEP对过度牵张的开始更敏感，并且比SEP更能有效指示截瘫。与SEP相比，NMEP应为外科医生提供更多时间来启动干预技术。由于NMEP和SEP提供了关于不同脊髓束的信息，作者在脊柱矫正手术期间继续使用这两种方法来监测人类脊髓的功能完整性。
