Netto E M, Marsden P D, Llanos-Cuentas E A, Costa J M, Cuba C C, Barreto A C, Badaró R, Johnson W D, Jones T C
Núcleo de Medicina Tropical e Nutrição, Universidade de Braília, Brazil.
Trans R Soc Trop Med Hyg. 1990 May-Jun;84(3):367-70. doi: 10.1016/0035-9203(90)90321-5.
Seventy-nine patients with cutaneous (62) or mucosal (17) infection with Leishmania (Viannia) braziliensis in Três Braços, Bahia, Brazil, were followed for at least 4 years after initiating treatment with antimony. Cutaneous relapses occurred in 6/62 (10%), mucosal relapse after cutaneous infection in 2/62 (3%), and mucosal relapse after mucosal disease in 2/17 (17%). It is concluded that relapse (cutaneous and mucosal) is rare after adequate antimony therapy and that no definite prediction of relapse (clinical, serological or by skin reaction) is possible.
在巴西巴伊亚州特雷斯布拉索斯，对79例皮肤（62例）或黏膜（17例）感染巴西利什曼原虫（维安尼亚种）的患者，在开始使用锑剂治疗后进行了至少4年的随访。62例皮肤感染患者中有6例（10%）出现皮肤复发，62例皮肤感染患者中有2例（3%）在皮肤感染后出现黏膜复发，17例黏膜疾病患者中有2例（17%）在黏膜疾病后出现黏膜复发。得出的结论是，经过充分的锑剂治疗后，复发（皮肤和黏膜）很少见，并且无法（通过临床、血清学或皮肤反应）对复发进行明确预测。
