Franková S, Mikulecká A
Institute of Physiology, Czechoslovak Academy of Sciences, Prague.
Act Nerv Super (Praha). 1990 Sep;32(3):167-73.
In pups of Wistar laboratory rats genetically selected for high (+A) and low (-A) locomotor activity in an open field social behavior was tested in a situation of paired interactions in a novel environment. Tests were performed on postnatal Days 16, 19, 23, and 27. They consisted of four five-minute trials with 50 min, intertrial intervals. Duration of active contacts, passive contacts, mutual grooming, following (chasing), and playful fighting was recorded. In pups of the +A line total duration of all social interactions increased between Days 16 and 23, while in the -A pairs preweaning maximum in most types of social activities was achieved already on Day 16, after this day the time spent in mutual contacts decreased. Analysis of dynamics of social behavior over trials in the -A line showed the tendency to habituate, maximum duration of paired interactions appeared in the first trial contrary to +A groups, in which duration of social contacts tended to increase with repeated trials. In both lines, duration of following responses increased from Day 16 to Day 27. In +A pairs following often led to playful fighting, while in -A pairs fighting was practically absent. The experiment demonstrated that differences between lines +A and -A appeared in those social contacts which required higher energy expenditure and which realized themselves in the larger space of the testing box.
在对开阔场地中高（+A）低（-A）运动活动进行基因选择的Wistar实验大鼠幼崽中，在新环境下的配对互动情境中测试社会行为。测试在出生后第16、19、23和27天进行。测试包括四次五分钟的试验，试验间隔为50分钟。记录主动接触、被动接触、相互梳理、跟随（追逐）和嬉戏打斗的持续时间。在+A品系的幼崽中，所有社会互动的总持续时间在第16天到23天之间增加，而在-A品系中，大多数社会活动在断奶前的第16天就达到了最大值，在这一天之后，相互接触所花费的时间减少。对-A品系试验中社会行为动态的分析表明有习惯化的趋势，与+A组相反，配对互动的最长持续时间出现在第一次试验中，在+A组中，社会接触的持续时间随着重复试验而趋于增加。在两个品系中，跟随反应的持续时间从第16天到第27天增加。在+A组中，跟随常常导致嬉戏打斗，而在-A组中几乎没有打斗。该实验表明，+A和-A品系之间的差异出现在那些需要更高能量消耗且在测试箱较大空间中实现的社会接触中。
