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A complicated simple fall--an atypical case of serogroup Y meningococcal pneumonia with secondary septicaemia and literature review.一例复杂的单纯性跌倒——Y群脑膜炎球菌肺炎继发败血症非典型病例及文献综述
BMJ Case Rep. 2012 Apr 4;2012:bcr1120115095. doi: 10.1136/bcr.11.2011.5095.
2
Meningococcal pneumonia: characterization and review of cases seen over the past 25 years.
Clin Infect Dis. 2000 Jan;30(1):87-94. doi: 10.1086/313617.
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Neisseria meningitidis W135 pneumonia with sepicaemia in a nonogenarian.一名九旬老人患W135群脑膜炎奈瑟菌肺炎合并败血症。
Scott Med J. 1998 Oct;43(5):148. doi: 10.1177/003693309804300508.
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Three cases of meningococcal pneumonia.三例脑膜炎球菌肺炎。
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University-acquired pneumonia.
Lancet Infect Dis. 2006 Mar;6(3):184. doi: 10.1016/S1473-3099(06)70416-9.
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Meningococcal pneumonia in Japan: A case report and literature review.日本的脑膜炎球菌肺炎:一例病例报告及文献综述
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[Meningococcemia and meningitis due to Neisseria meningitidis W135 developed in two cases vaccinated with bivalent (A/C) meningococcal vaccine].两例接种二价(A/C)脑膜炎球菌疫苗的患者发生了由W135群脑膜炎奈瑟菌引起的脑膜炎球菌血症和脑膜炎。
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Australian Meningococcal Surveillance Programme annual report, 2013.《2013年澳大利亚脑膜炎球菌监测计划年度报告》
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A premature infant with fulminant meningococcal septicaemia.一名患有暴发性脑膜炎球菌败血症的早产儿。
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引用本文的文献

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Meningococcal pneumonia: a review.脑膜炎球菌性肺炎:综述
Pneumonia (Nathan). 2019 Aug 25;11:3. doi: 10.1186/s41479-019-0062-0. eCollection 2019.

本文引用的文献

1
Meningococcal pneumonia: characterization and review of cases seen over the past 25 years.
Clin Infect Dis. 2000 Jan;30(1):87-94. doi: 10.1086/313617.
2
Serogroup Y meningococcal disease in Chicago, 1991-1997.1991 - 1997年芝加哥Y群脑膜炎球菌病
JAMA. 1998;280(24):2094-8. doi: 10.1001/jama.280.24.2094.
3
Meningococcal disease in New York City, 1973 to 1978. Recognition of groups y and W-135 as frequent pathogens.1973年至1978年纽约市的脑膜炎球菌病。确认Y群和W-135群为常见病原体。
JAMA. 1980 Nov 14;244(19):2167-71.
4
Meningitis, pneumonitis, and arthritis caused by Neisseria meningitidis group Y.由Y群脑膜炎奈瑟菌引起的脑膜炎、肺炎和关节炎。
JAMA. 1975 Jun 30;232(13):1354-5.

一例复杂的单纯性跌倒——Y群脑膜炎球菌肺炎继发败血症非典型病例及文献综述

A complicated simple fall--an atypical case of serogroup Y meningococcal pneumonia with secondary septicaemia and literature review.

作者信息

Chan B K Y, Kudsk-Iversen S, Balaguruswamy S, Purewal T S

机构信息

Department of Endocrinology and General Medicine, Royal Liverpool University Hospital, Liverpool, UK.

出版信息

BMJ Case Rep. 2012 Apr 4;2012:bcr1120115095. doi: 10.1136/bcr.11.2011.5095.

DOI:10.1136/bcr.11.2011.5095
PMID:22604203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3339171/
Abstract

An elderly lady was admitted for pain management and rehabilitation following a fall. During her stay she developed a new heart murmur and sepsis. Subacute bacterial endocarditits was excluded, empirical ciprofloxacin was initiated and later converted to aztreonam with gentamicin for clinical deterioration. Subsequent investigations revealed meningococcal Y septicaemia secondary to pneumonia, with a possible oropharynx focus. Upon discharge she had returned to baseline state. The case reflects an unusual and increasing cause of pneumonia. A steady increase of infective serogroup Y isolates over the past 12-years in England, with tendency towards elderly makes it a significant differential among the general medical population. This trend corresponds with the US, but is yet unknown whether to be a periodic cycle or true change in dominance and, or, virulence among serogroups. If the latter were true, it would support the inclusion of serogroups beyond menigitides C in the vaccination program.

摘要

一位老年女性因跌倒后进行疼痛管理和康复治疗而入院。住院期间,她出现了新的心脏杂音和败血症。排除了亚急性细菌性心内膜炎,开始经验性使用环丙沙星,后来因临床病情恶化改用氨曲南联合庆大霉素。随后的检查发现,肺炎继发脑膜炎球菌Y败血症,可能的感染源为口咽部。出院时她已恢复到基线状态。该病例反映了一种不常见且日益增多的肺炎病因。在过去12年里,英格兰感染性Y血清群分离株稳步增加,且发病倾向于老年人,这使其成为普通内科人群中一个重要的鉴别诊断因素。这种趋势与美国一致,但尚不清楚这是一个周期性循环,还是血清群之间优势地位和/或毒力的真正变化。如果是后者,将支持在疫苗接种计划中纳入除C群脑膜炎球菌之外的血清群。