Galaid E I, Cherubin C E, Marr J S, Schaefler S, Barone J, Lee W
JAMA. 1980 Nov 14;244(19):2167-71.
In the period 1973 through 1978, the New York City Department of Health serogrouped 648 isolates of Neisseria meningitidis and investigated 259 cases if meningococcal meningitis and meningococcemia. Although meningitis and septicemia were mainly due to groups B and C, groups Y and W-135 caused nearly one third of the cases. There was no difference in mortalities when disease caused by the classic groups A, B, and C was compared with disease caused by the new serogroups X, Y, Z, W-135, and Z'. Most isolates from the respiratory tract were from the new serogroups, especially Z and Z' (some from patients with pneumonia), as were most of those from the genitourinary tract, anal canal, and miscellaneous sites. Group X was infrequently seen. Although most of the isolations of these groups of N meningitidis are apparently from asymptomatic carriers, Y and W-135 do cause a substantial number of acute symptomatic infections, in particular, septicemia.
在1973年至1978年期间，纽约市卫生部门对648株脑膜炎奈瑟菌进行了血清分组，并对259例脑膜炎球菌性脑膜炎和脑膜炎球菌血症病例进行了调查。虽然脑膜炎和败血症主要由B群和C群引起，但Y群和W-135群导致了近三分之一的病例。将由经典的A、B和C群引起的疾病与由新血清群X、Y、Z、W-135和Z'引起的疾病相比较，死亡率没有差异。呼吸道的大多数分离株来自新血清群，尤其是Z群和Z'（有些来自肺炎患者），泌尿生殖道、肛管和其他部位的大多数分离株也是如此。X群很少见。虽然这些脑膜炎奈瑟菌群的大多数分离株显然来自无症状携带者，但Y群和W-135群确实会引起大量急性症状性感染，尤其是败血症。
