Colombo E, Bimbi G, Gelosa G, Brusamolino R
Divisione di Otorinolaringoiatria dell'Ospedale Niguarda Cà Granda di Milano.
Acta Otorhinolaryngol Ital. 1990 Mar-Apr;10(2):121-7.
The authors report a pathological study of functional neck dissection performed on 145 N0 laryngeal carcinoma patients from 1982 to 1988. The incidence of occult latero-cervical metastases in N0 was evaluated in relation to site and extension of the primitive tumor. A total of 108 supraglottic, 25 glottic and 12 transglottic tumors were observed. Among the cases treated the incidence of occult metastases was 28.3% while capsular rupture accounted for 3.4%. Diagnostic error, calculated on the number of neck dissections, was 20.2%. A greater incidence of occult metastases was found in supraglottic tumors (29.6%) than in either glottic (24%) or transglottic (25%) tumors. Furthermore, incidence of occult metastases proved proportional to the extension of the primitive tumor. There was a single metastases in 35 cases while only 6 cases proved multiple. Some final considerations are given on the importance of performing precautionary functional neck dissection in N0 laryngeal cancer.
作者报告了1982年至1988年对145例N0期喉癌患者进行功能性颈清扫术的病理学研究。评估了N0期隐匿性颈侧转移的发生率与原发肿瘤部位及范围的关系。共观察到108例声门上型、25例声门型和12例跨声门型肿瘤。在接受治疗的病例中,隐匿性转移的发生率为28.3%,而包膜破裂占3.4%。根据颈清扫术的数量计算,诊断错误率为20.2%。声门上型肿瘤(29.6%)隐匿性转移的发生率高于声门型(24%)或跨声门型(25%)肿瘤。此外,隐匿性转移的发生率与原发肿瘤的范围成正比。35例为单发转移,而仅有6例为多发转移。文中对N0期喉癌预防性功能性颈清扫术的重要性给出了一些最终的思考。