摄入氯喹后出现危及生命的急性高铁血红蛋白血症。
Acute life-threatening methaemoglobinaemia following ingestion of chloroquine.
作者信息
Rizvi Imran, Zaman Shamsuz, Zaidi Noorin, Asif Mohammed S, Abdali Nasar
机构信息
General Medicine Department, J N Medical College, Aligarh, UP, India.
出版信息
BMJ Case Rep. 2012 Mar 20;2012:bcr1220115383. doi: 10.1136/bcr.12.2011.5383.
Abstract
A 25 year old man was rushed to the emergency department when he was found unconscious in his room after taking two chloroquine tablets (600 mg base) for fever prescribed by local practitioner. On examination, the patient was unconscious and deep cyanosis was present on lips, tongue, oral cavity, nail beds and finger tips. Subsequent laboratory investigation revealed methaemoglobin level of 54%. Diagnosis of chloroquine-induced methaemoglobinaemia was made and methylene blue (1 mg/kg) was administered. The patient improved dramatically and was discharged following day.
摘要
一名25岁男子在按照当地医生的处方服用两片氯喹片（600毫克碱）治疗发烧后，被发现昏迷在自己房间，随后被紧急送往急诊科。检查时，患者昏迷，嘴唇、舌头、口腔、甲床和指尖出现深紫绀。随后的实验室检查显示高铁血红蛋白水平为54%。诊断为氯喹诱发的高铁血红蛋白血症，并给予亚甲蓝（1毫克/千克）治疗。患者病情显著改善，次日出院。
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