Kragsfeldt Celina Thelberg, Nissen Christoffer B, Brandt Frans
Ugeskr Laeger. 2016 Aug 22;178(34).
We present a case report of an 18-year-old male who was referred to the emergency department with evidence of methaemoglobinaemia. He presented with classic symptoms with peripheral cyanosis and hypoxia. Arterial blood gas showed a methaemoglobin level of 36%. This was caused by ingestion of alkyl nitrate, a widespread party drug called "poppers". When inhaled it causes euphoria, reduced pain and relaxation of the anal sphincter, but oral use may induce life-threatening methaemoglobinaemia. The treatment of choice is the antidote methylene blue. After treatment the patient regained full recovery and was discharged on the following day. We discuss classic symptoms, diagnosis and treatment of intoxication with methylene blue.
我们报告一例18岁男性病例,该患者因高铁血红蛋白血症被转诊至急诊科。他表现出外周发绀和缺氧的典型症状。动脉血气显示高铁血红蛋白水平为36%。这是由于摄入烷基硝酸盐所致,烷基硝酸盐是一种名为“Poppers”的广泛使用的派对药物。吸入时会引起欣快感、减轻疼痛并使肛门括约肌松弛,但口服可能会诱发危及生命的高铁血红蛋白血症。治疗的首选药物是解毒剂亚甲蓝。治疗后患者完全康复,次日出院。我们讨论了亚甲蓝中毒的典型症状、诊断和治疗。