Accidental intrathecal injection of tranexamic Acid.
作者信息
Mahmoud Khaled, Ammar Amany
机构信息
Faculty of Medicine, Minoufiya University, Shebin El Kom, Minoufiya 32511, Egypt.
出版信息
Case Rep Anesthesiol. 2012;2012:646028. doi: 10.1155/2012/646028. Epub 2012 Mar 26.
Abstract
Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from similarities in appearance between TXA and heavy bupivacaine 0.5% ampoules. The patient experienced severe pain in the back and gluteal region upon injection in association with systemic hypertension and tachycardia followed by generalized myoclonic seizures and ventricular fibrillation.
摘要
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