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微创减压与稳定术治疗胸腰椎转移瘤。

Minimally invasive decompression and stabilization for the management of thoracolumbar spine metastasis.

机构信息

Department of Neurosurgery, Lille University Hospital, Rue Emile Laine, Lille, France.

出版信息

J Neurosurg Spine. 2012 Jul;17(1):19-23. doi: 10.3171/2012.4.SPINE111108. Epub 2012 May 18.

Abstract

OBJECT

Spinal metastasis with spinal cord involvement is a frequent complication in cancer patients. As the spinal compression frequently occurs ventrally, performing a simple posterior laminectomy alone is generally ineffective and dangerous. Many aggressive surgical strategies have been developed to improve outcomes for patients with metastatic spine disease. These strategies are associated with high morbidity and complication rates, especially in patients with numerous neoplasm-associated comorbidities, which can limit their indication in patients with a limited life expectancy. The authors performed a prospective evaluation of minimally invasive decompression and stabilization for the palliative management of symptomatic thoracolumbar spine metastasis.

METHODS

Ten patients with metastasis to the thoracolumbar spine and neurological compromise underwent minimally invasive transpedicular vertebrectomy and spinal cord decompression through a tubular expandable retractor. Percutaneous stabilization was also systematically performed to ensure spinal stability.

RESULTS

No complications during the procedure were reported. The mean operative duration was 170 minutes and the mean estimated blood loss was 400 ml. The postoperative course of all patients was uneventful, with the exception of 1 benign urinary tract infection. Eight patients (80%) improved at least 1 Frankel grade.

CONCLUSIONS

Minimally invasive treatment of thoracolumbar spine metastasis is a safe and effective palliative option in patients with limited life expectancy, to limit morbidity and preserve quality of life.

摘要

目的

脊柱转移合并脊髓受累是癌症患者常见的并发症。由于脊柱压缩通常发生在脊柱的前侧,因此单纯进行简单的后路椎板切除术通常是无效且危险的。许多积极的手术策略已被开发出来,以改善转移性脊柱疾病患者的预后。这些策略与高发病率和并发症发生率相关,尤其是在患有多种与肿瘤相关的合并症的患者中,这可能会限制其在预期寿命有限的患者中的适应证。作者对微创减压和稳定术治疗胸腰椎转移引起的症状性脊柱进行了前瞻性评估。

方法

10 例胸腰椎转移并伴有神经功能障碍的患者接受了微创经椎弓根椎体切除术和管状可扩张牵开器进行脊髓减压。还系统地进行了经皮稳定术,以确保脊柱稳定。

结果

手术过程中无并发症发生。平均手术时间为 170 分钟,平均估计失血量为 400ml。除 1 例良性尿路感染外,所有患者的术后过程均平稳。8 例(80%)患者至少提高了 1 个 Frankel 分级。

结论

对于预期寿命有限的患者,微创治疗胸腰椎转移是一种安全有效的姑息治疗选择,可以限制发病率并保持生活质量。

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