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经皮椎弓根螺钉内固定联合可扩张通道牵开器治疗脊柱转移瘤

[Percutaneous pedicle screw fixation combined expandable tubular retractor in the treatment of spinal metastases].

作者信息

Cui Y P, Shi X D, Liu J, Mi C, Wang B, Pan Y X, Lin Y F

机构信息

Department of Orthopaedics, Peking University First Hospital, Beijing 100034, China.

Department of Radiology, Peking University First Hospital, Beijing 100034, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2023 Jun 18;55(3):530-536. doi: 10.19723/j.issn.1671-167X.2023.03.020.

Abstract

OBJECTIVE

To investigate the effectiveness of percutaneous pedicle screw fixation combined expandable tubular retractor in the treatment of patients with spinal metastases.

METHODS

In the study, 12 patients of spinal metastases treated with percutaneous pedicle screw fixation combined expandable tubular retractor in our hospital were retrospectively reviewed between June 2017 and October 2019. Among the 12 patients, 9 were males and 3 were females; the median age was 62.5 years [(65.1±2.9) years]. The decompression segment of 7 patients was located at the lower thoracic spine (including 1 patient with incomplete paraplegia) and the decompression segment of 5 patients was located at the lumbar spine; Tomita score was 6.0±0.6. Perioperative data of the patients were reviewed. Visual analog scale (VAS score), Karnofsky score, and Eastern Cooperative Oncology Group (ECOG) score were compared before and after surgery. The patient's survival, adjuvant treatment, and internal fixation failure were observed in the follow-up period.

RESULTS

All the 12 patients had a successful operation with percuta-neous pedicle screw fixation combined expandable tubular retractor. The average operative time, blood loss, and blood transfused of the patients were (247.0±14.6) min, (804.2±222.3) mL and (500.0±100.0) mL, respectively. The average amount of drainage was (240.8±79.3) mL. Drainage tubes were pulled out early postoperative [(3.2±0.3) d], allowing early mobilization. The patients discharged (7.8±0.8) d postoperative. All the patients were followed up for 6-30 months, and the average overall survival time was (13.6±2.4) months. During the follow-up period, 2 patients experienced screw displacement, the internal fixation was stable after conservative treatment and no revision surgery was performed. The VAS of the patients was 7.1±0.2 before surgery, which decreased to 2.3±0.1 and 2.8±0.4 at 3 and 6 months after surgery ( < 0.05). The Karnofsky score of the patients was 59.2±1.9 before surgery, which increased to 75.0±1.9 and 74.2±3.1 at 3 and 6 months after surgery ( < 0.05). The ECOG of the patients was 2.3±0.2 before surgery, which decreased to 1.7±0.1 and 1.7±0.2 at 3 and 6 months after surgery ( < 0.05).

CONCLUSION

For selected patients with spinal metastases, minimally invasive surgical treatment of spinal metastases (percutaneous pedicle screw internal fixation combined with expandable tubular retractor) can effectively relieve the clinical symptoms and improve the quality of life, with satisfactory clinical outcome.

摘要

目的

探讨经皮椎弓根螺钉内固定联合可扩张通道撑开器治疗脊柱转移瘤患者的疗效。

方法

回顾性分析2017年6月至2019年10月在我院接受经皮椎弓根螺钉内固定联合可扩张通道撑开器治疗的12例脊柱转移瘤患者。12例患者中,男性9例,女性3例;中位年龄62.5岁[(65.1±2.9)岁]。7例患者减压节段位于胸下段脊柱(其中1例不完全性截瘫),5例患者减压节段位于腰椎;Tomita评分6.0±0.6。回顾患者围手术期资料。比较手术前后视觉模拟评分(VAS评分)、卡氏评分及东部肿瘤协作组(ECOG)评分。随访观察患者生存情况、辅助治疗及内固定失败情况。

结果

12例患者均成功实施经皮椎弓根螺钉内固定联合可扩张通道撑开器手术。患者平均手术时间、出血量及输血量分别为(247.0±14.6)分钟、(804.2±222.3)毫升和(500.0±100.0)毫升。平均引流量为(240.8±79.3)毫升。术后早期(3.2±0.3)天拔除引流管,可早期活动。患者术后(7.8±0.8)天出院。所有患者随访6 - 30个月,平均总生存时间为(13.6±2.4)个月。随访期间,2例患者出现螺钉移位,经保守治疗后内固定稳定,未行翻修手术。患者术前VAS评分为7.1±0.2,术后3个月和6个月分别降至2.3±0.1和2.8±0.4(P<0.05)。患者术前卡氏评分为59.2±1.9,术后3个月和6个月分别升至75.0±1.9和74.2±3.1(P<0.05)。患者术前ECOG评分为(2.3±0.2),术后3个月和6个月分别降至1.7±0.1和1.7±0.2(P<0.05)。

结论

对于选择合适的脊柱转移瘤患者,微创治疗脊柱转移瘤(经皮椎弓根螺钉内固定联合可扩张通道撑开器)能有效缓解临床症状,提高生活质量,临床效果满意。

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