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绝经症状:生活事件是否可预测绝经前和绝经后症状的严重程度?

Menopausal symptoms: do life events predict severity of symptoms in peri- and post-menopause?

机构信息

Psychology and Health Research Unit, ISPA-Instituto Universitário, Portugal.

出版信息

Maturitas. 2012 Aug;72(4):324-31. doi: 10.1016/j.maturitas.2012.04.006. Epub 2012 May 17.

Abstract

OBJECTIVE

Hormonal changes during menopausal transition are linked to physical and psychological symptoms' emergence. This study aims to explore if life events predict menopausal symptoms.

METHODS

This cross-sectional research encompasses a community sample of 992 women who answered to socio-demographic, health, menopause-related and lifestyle questionnaires; menopausal symptoms and life events were assessed with validated instruments. Structural equation modeling was used to build a causal model.

RESULTS

Menopausal status predicted only three symptoms: skin/facial hair changes (β=.136; p=.020), sexual (β=.157; p=.004) and, marginally, vasomotor symptoms (β=.094; p=.054). Life events predicted depressive mood (β=-.391; p=.002), anxiety (β=-.271; p=.003), perceived cognitive impairment (β=-.295; p=.003), body shape changes (β=-.136; p=.031), aches/pain (β=-.212; p=.007), skin/facial hair changes (β=-.171; p=.021), numbness (β=-.169; p=.015), perceived loss of control (β=-.234; p=.008), mouth, nails and hair changes (β=-.290; p=.004), vasomotor (β=-.113; p=.044) and sexual symptoms (β=-.208; p=.009).

CONCLUSIONS

Although women in peri- and post-menopausal manifested higher symptoms' severity than their pre-menopausal counterparts, only three of the menopausal symptoms assessed were predicted by menopausal status. Since the vast majority of menopausal symptoms' severity was significantly influenced by the way women perceived their recent life events, it is concluded that the symptomatology exacerbation, in peri- and post-menopausal women, might be due to life conditions and events, rather than hormonal changes (nonetheless, the inverse influence should be investigated in future studies). Therefore, these should be accounted for in menopause-related clinical and research settings.

摘要

目的

更年期过渡期间的激素变化与身体和心理症状的出现有关。本研究旨在探讨生活事件是否可以预测更年期症状。

方法

这项横断面研究包括了一个社区样本,共 992 名女性回答了社会人口统计学、健康、与绝经相关和生活方式问卷;使用经过验证的工具评估了更年期症状和生活事件。结构方程模型用于构建因果模型。

结果

绝经状态仅预测了三种症状:皮肤/面部毛发变化(β=.136;p=.020)、性(β=.157;p=.004),以及血管舒缩症状(β=.094;p=.054)。生活事件预测了抑郁情绪(β=-.391;p=.002)、焦虑(β=-.271;p=.003)、认知障碍感知(β=-.295;p=.003)、体型变化(β=-.136;p=.031)、疼痛(β=-.212;p=.007)、皮肤/面部毛发变化(β=-.171;p=.021)、麻木(β=-.169;p=.015)、失控感(β=-.234;p=.008)、口腔、指甲和头发变化(β=-.290;p=.004)、血管舒缩(β=-.113;p=.044)和性症状(β=-.208;p=.009)。

结论

虽然处于绝经前期和绝经后期的女性表现出比绝经前女性更高的症状严重程度,但只有三种评估的更年期症状与绝经状态有关。由于大多数更年期症状的严重程度受到女性对近期生活事件的感知方式的显著影响,因此可以得出结论,绝经前期和绝经后期女性的症状恶化可能是由于生活条件和事件引起的,而不是激素变化(尽管如此,在未来的研究中应该调查这种相反的影响)。因此,在与绝经相关的临床和研究环境中应考虑到这些因素。

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