Sobell Department of Motor Neuroscience and Movement Disorders, University College London, London WC1N 3BG, UK.
Clin Neurophysiol. 2012 Nov;123(11):2296-305. doi: 10.1016/j.clinph.2012.04.006. Epub 2012 May 17.
To examine the validity of multi-fiber muscle velocity recovery cycles (VRCs) recorded by direct muscle stimulation with submaximal stimuli.
VRCs were recorded from tibialis anterior muscle in normal volunteers with 1, 2 and 5 conditioning stimuli. Recordings were made with 6 different amplitudes of conditioning stimuli. Recordings were also made with two recording electrodes, at least 15mm apart.
Muscle VRCs in 6 subjects were not significantly different for conditioning stimuli between 80% and 150% of test stimulus amplitude. When recorded at two sites in 9 subjects, VRCs were similar when estimated over the shorter distance, the longer distance, and from the conduction time between the two electrodes.
Multi-fiber muscle VRCs can be reliably recorded with a single recording electrode and with equal amplitude conditioning and test stimuli.
Clinical neurophysiologists can be assured that this new method of testing muscle membrane properties provides valid and robust measurements on normal muscles.
研究用亚最大刺激直接刺激记录的多纤维肌速度恢复循环（VRC）的有效性。
用 1、2 和 5 个条件刺激在正常志愿者的胫骨前肌上记录 VRC。用 6 种不同的条件刺激幅度进行记录。还使用两个记录电极进行记录，电极之间至少相隔 15mm。
6 名受试者的肌肉 VRC 对于测试刺激幅度在 80%至 150%之间的条件刺激没有显著差异。在 9 名受试者的两个部位进行记录时，当在较短距离、较长距离和两个电极之间的传导时间进行估计时，VRC 相似。
可以用单个记录电极和相等幅度的条件刺激和测试刺激可靠地记录多纤维肌 VRC。
临床神经生理学家可以放心，这种测试肌肉膜特性的新方法可以对正常肌肉进行有效和可靠的测量。
