肌肉速度恢复周期：重复刺激对两块肌肉的影响。
Muscle velocity recovery cycles: effects of repetitive stimulation on two muscles.
机构信息
Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
出版信息
Muscle Nerve. 2012 Jul;46(1):102-11. doi: 10.1002/mus.23267.
INTRODUCTION
We sought to characterize the excitability properties of tibialis anterior (TA) and brachioradialis (BR) muscles at rest and during electrically induced muscle activation in normal subjects.
METHODS
Two centers recruited 10 subjects each. Multi-fiber velocity recovery cycles (VRCs) were recorded from TA (both centers) and BR (one center). VRCs were assessed at rest and during repetitive stimulation (intermittent 20 Hz for 6 min). Changes in latency and peak amplitude of the muscle action potential induced by a frequency ramp to 30 Hz were also characterized.
RESULTS
Excitability properties recorded from TA were very similar between centers. Repetitive stimulation generated marked excitability changes, which were similar between TA and BR.
CONCLUSIONS
Standardized tests of muscle VRCs and responses to repetitive stimulation can provide consistent measures of membrane function and may encourage their wider use in clinical neurophysiology to investigate the pathophysiology of neuromuscular disorders.
简介
我们旨在描述正常受试者在休息时和电刺激肌肉激活时胫骨前肌（TA）和肱桡肌（BR）的兴奋性特征。
方法
两个中心各招募了 10 名受试者。从 TA（两个中心）和 BR（一个中心）记录多纤维速度恢复循环（VRC）。在休息时和重复刺激（6 分钟间歇性 20 Hz）期间评估 VRC。还描述了频率斜坡至 30 Hz 引起的肌肉动作电位潜伏期和峰值幅度的变化。
结果
从 TA 记录的兴奋性特征在两个中心之间非常相似。重复刺激产生了明显的兴奋性变化，这些变化在 TA 和 BR 之间是相似的。
结论
肌肉 VRC 和重复刺激反应的标准化测试可以提供膜功能的一致测量值，并可能鼓励它们在临床神经生理学中更广泛地用于研究神经肌肉疾病的病理生理学。
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