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[应用CAP系统对儿童过敏患者特异性IgE抗体的研究]

[Study on specific IgE antibodies in pediatric allergic patients by CAP system].

作者信息

Sumimoto S, Kawi M, Kasajima Y, Hamamoto T

机构信息

Department of Pediatrics, Sumitomo Hospital.

出版信息

Arerugi. 1990 Oct;39(10):1416-21.

PMID:2260929
Abstract

The CAP system is a new method to detect specific IgE antibodies and is an advanced method of the traditional paper disc RAST. Our result suggests a significant correlation between scores obtained with the CAP system and those with the traditional RAST. Since specific IgE antibodies against multiple allergens can be measured with the CAP system, we studied 5 food allergen specific IgE antibodies (Fx5) in cases of infantile atopic dermatitis. This study indicates a good correlation between the Fx5 scores and clinical symptoms of these patients. Thus, it is concluded that the CAP system is useful for screening IgE antibodies against multiple food allergens in cases of infantile atopic dermatitis.

摘要

CAP系统是一种检测特异性IgE抗体的新方法,是传统纸碟RAST的先进方法。我们的结果表明,CAP系统获得的分数与传统RAST获得的分数之间存在显著相关性。由于CAP系统可以检测多种过敏原的特异性IgE抗体,我们研究了婴儿特应性皮炎患者的5种食物过敏原特异性IgE抗体(Fx5)。本研究表明Fx5分数与这些患者的临床症状之间具有良好的相关性。因此,得出结论,CAP系统可用于筛查婴儿特应性皮炎患者针对多种食物过敏原的IgE抗体。

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