Sabbah A, Solier C, Lauret M G, Drouet M
Laboratoire d'Immuno-allergologie, CHRU, Angers.
Allerg Immunol (Paris). 1992 Sep;24(7):253-5.
A comparative study was made of three in vivo and in vitro diagnostic methods for food allergy: Fx5 multitest (Pharmacia); Measurement of specific IgE CAP (Pharmacia); Skin tests (Prick Tests). 20 patients, from 3 to 71 years (mean 24.4 years), were selected by clinical suggestion (asthma, rhinitis, atopic dermatitis, urticaria and/or Quincke's oedema). The Fx5 test used six food allergens: wheat, egg, cow's milk, soya, peanut and fish. The Cap Rast for each substance was evaluated, as was Fx5, by a radio-immunological method. The Prick Tests made with the six allergens used were considered to be positive when the diameter of the weal was greater than that produced by a reference test with histamine. The results were considered as a comparison between Fx5 and Cap Rast to each of the foods, between Fx5 and prick Test with five foods and finally between CAP RAST and Prick Test. Correlation Fx5--Cap rast was better and more useful in the diagnosis of food allergy than skin tests.
Fx5多项检测（法玛西亚公司）；特异性IgE CAP检测（法玛西亚公司）；皮肤试验（点刺试验）。通过临床指征（哮喘、鼻炎、特应性皮炎、荨麻疹和/或昆克水肿）选取了20名患者，年龄在3至71岁之间（平均24.4岁）。Fx5检测使用了六种食物过敏原：小麦、鸡蛋、牛奶、大豆、花生和鱼。每种物质的CAP RAST检测以及Fx5检测均通过放射免疫法进行评估。当使用六种过敏原进行点刺试验产生的风团直径大于用组胺进行的对照试验产生的风团直径时，该点刺试验被视为阳性。结果被视为Fx5与每种食物的CAP RAST之间的比较、Fx5与五种食物的点刺试验之间的比较，以及最终CAP RAST与点刺试验之间的比较。在食物过敏诊断中，Fx5与CAP RAST的相关性比皮肤试验更好且更有用。
