Department of Orthopedic Surgery, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Arch Orthop Trauma Surg. 2012 Sep;132(9):1251-7. doi: 10.1007/s00402-012-1545-0. Epub 2012 May 18.
Psychological distress may be an important determinant of perceived disability in patients with chronic musculoskeletal disorders. We evaluated the relationship between depressive symptoms and perceived disability in patients with chronic shoulder pain and quantified the contribution made by depression to perceived disability.
In this prospective study, 109 patients with chronic shoulder pain caused by degenerative or inflammatory disorders were evaluated using the Disability of Arm, Shoulder and Hand (DASH) questionnaire and the Center for Epidemiologic Studies-Depression (CES-D) Scale to determine relationships between depressive symptoms and perceived disability in patients with chronic shoulder pain. In addition, pain scores were evaluated using a visual analog scale (VAS) during activity, and range of motion (ROM) and abduction strength (strength) measurements were measured. Multivariate analyses of variance and regression modeling were used to assess the relative contributions made by depressive symptoms (CES-D) and other clinical parameters to patient-perceived disability (DASH).
DASH scores were found to be moderately correlated (0.3 < r < 0.6) with ROM, strength, pain VAS and CES-D; DASH scores were more strongly correlated with CES-D scores than with pain VAS scores or range of motion (r = 0.58; p < 0.001, 0.37; p < 0.001, 0.32; p = 0.04 respectively). Multiple stepwise regression analyses revealed that gender, ROM, pain VAS and CES-D scores independently predicted DASH score and accounted for 43 % of the variance. CES-D score was found to be the strongest predictor of DASH score and accounted for 23 % of the variance.
Degrees of depressive symptoms were found to be significantly associated with higher symptom scores and greater disability in patients with chronic shoulder pain. Although a large proportion of perceived disability remains unexplained, perceived disability in patients with chronic shoulder pain was found to be strongly influenced by depressive symptoms.
TYPE OF STUDY/LEVEL OF EVIDENCE: Level 2, prospective cohort study, prognostic study.
心理困扰可能是慢性肌肉骨骼疾病患者感知残疾的一个重要决定因素。我们评估了抑郁症状与慢性肩痛患者感知残疾之间的关系,并量化了抑郁对感知残疾的贡献。
在这项前瞻性研究中,对 109 例由退行性或炎症性疾病引起的慢性肩痛患者进行评估,使用上肢功能障碍问卷(DASH)和流行病学研究中心抑郁量表(CES-D)来确定慢性肩痛患者抑郁症状与感知残疾之间的关系。此外,在活动期间使用视觉模拟量表(VAS)评估疼痛评分,测量关节活动度(ROM)和外展力量(强度)。使用方差分析和回归建模进行多变量分析,以评估抑郁症状(CES-D)和其他临床参数对患者感知残疾(DASH)的相对贡献。
DASH 评分与 ROM、强度、疼痛 VAS 和 CES-D 中度相关(0.3<r<0.6);DASH 评分与 CES-D 评分的相关性强于疼痛 VAS 评分或 ROM(r=0.58;p<0.001,0.37;p<0.001,0.32;p=0.04)。多元逐步回归分析显示,性别、ROM、疼痛 VAS 和 CES-D 评分独立预测 DASH 评分,解释了 43%的方差。CES-D 评分是 DASH 评分的最强预测因子,解释了 23%的方差。
抑郁症状的严重程度与慢性肩痛患者的症状评分更高和残疾程度更大显著相关。尽管大部分感知残疾仍无法解释,但慢性肩痛患者的感知残疾受抑郁症状的强烈影响。
研究类型/证据水平:2 级,前瞻性队列研究,预后研究。