Bhattacharya Anjanabha, Kumar Anish, Desai Nirali, Parikh Seema
National Environmental Sound Production Agriculture Laboratory, University of Georgia, Tifton, GA, USA.
Methods Mol Biol. 2012;877:401-6. doi: 10.1007/978-1-61779-818-4_29.
The source of genetic information in a plant cell is contained in nucleus, plastids, and mitochondria. Organelle transformation is getting a lot of attention nowadays because of its superior performance over the conventional and most commonly used nuclear transformation for obtaining transgenic lines. Absence of gene silencing, strong predictable transgene expression, and its application in molecular pharming, both in pharmaceutical and nutraceuticals, are some of many advantages. Other important benefits of utilizing this technology include the absence of transgene flow, as organelles are maternally inherited. This may increase the acceptability of organelle transformation technology in the development of transgenic crops in a wider scale all over the globe. As the need for crop productivity and therapeutic compounds increases, organelle transformation may be able to bridge the gap, thereby having a definite promise for the future.
植物细胞中遗传信息的来源包含在细胞核、质体和线粒体中。细胞器转化如今备受关注，因为相较于传统且最常用的核转化以获得转基因品系，它具有卓越的性能。不存在基因沉默、强大且可预测的转基因表达，以及其在分子制药（包括药物和营养保健品）中的应用，这些都是众多优势中的一部分。利用该技术的其他重要益处包括不存在转基因漂移，因为细胞器是母系遗传的。这可能会提高细胞器转化技术在全球更广泛范围内转基因作物开发中的可接受性。随着对作物产量和治疗性化合物需求的增加，细胞器转化或许能够填补这一空白，从而对未来有着明确的前景。
