Gauchan E, Malla T, Basnet S, Rao K S
Department of Pediatrics, Manipal Teaching Hospital, Pokhara, Nepal.
Kathmandu Univ Med J (KUMJ). 2011 Apr-Jun;9(34):17-21. doi: 10.3126/kumj.v9i2.6281.
Neurocysticercosis is one of the common neurological morbidities in childhood.
To find the commonest mode of presentation of this disorder in children. The study also aims to find out the age at which it commonly occurs, commonest site affected in the brain and the ethnic group and region most commonly affected in Western Nepal.
Retrospective hospital based study carried out in the Department of Pediatrics, Manipal Teaching Hospital, Pokhara from June 2004 to June 2009.
Over the period of five years, 678 patients were admitted for seizures; out of which 109 patients were diagnosed as having neurocysticercosis (16%). Out of them, 66 (60.5%) were males and 43 (39.4%) were females. The age of presentation varied from 18 months to 16 years, with mean age 9.77 years. The most common age of presentation was between 6-10 years (n=47; 43.1%) and 11-15 years (n=47; 43.1%). Maximum number of patients were from Kaski district (n=41; 37.6%) followed by Syangja (n=34; 31.1%).The commonest presentation was with seizures (n=85; 77.9 %); generalised seizures was present in 45 patients (52%). Psychiatric manifestations were present in 3 patients (2.7%). The lesions were found mostly in the parietal region (n=65; 59.6 %). Most of the lesions were single (n=89; 81.6%). Out of 109 patients, 74 patients (67.8%) improved without any recurrence of symptoms on two years follow-up.
Neurocysticercosis is a preventable zoonotic disease which results in significant morbidity in children where sanitary measures are inadequate. Any child presenting with a first episode, afebrile seizure should be screened for neurocysticercosis provided other common causes are ruled out.
神经囊尾蚴病是儿童常见的神经系统疾病之一。
找出儿童期该疾病最常见的表现形式。该研究还旨在确定其通常发病的年龄、大脑中最常受影响的部位以及尼泊尔西部最常受影响的种族和地区。
2004年6月至2009年6月在博卡拉马尼帕尔教学医院儿科进行的基于医院的回顾性研究。
在五年期间，678例患者因癫痫发作入院；其中109例被诊断为神经囊尾蚴病（16%）。其中，66例（60.5%）为男性，43例（39.4%）为女性。发病年龄从18个月至16岁不等，平均年龄9.77岁。最常见的发病年龄在6至10岁（n = 47；43.1%）和11至15岁（n = 47；43.1%）之间。患者人数最多的是卡斯库区（n = 41；37.6%），其次是桑贾区（n = 34；31.1%）。最常见的表现是癫痫发作（n = 85；77.9%）；45例患者（52%）出现全身性癫痫发作。3例患者（2.7%）有精神症状。病变大多位于顶叶区域（n = 65；59.6%）。大多数病变为单个（n = 89；81.6%）。在109例患者中，74例（67.8%）在两年随访中症状改善且无复发。
神经囊尾蚴病是一种可预防的人畜共患病，在卫生措施不完善的地区会导致儿童出现严重发病情况。任何首次出现无热惊厥的儿童，在排除其他常见病因后，都应进行神经囊尾蚴病筛查。
