Department of Cardiac Surgery, Leipzig University Heartcentre, Leipzig, Germany.
Eur J Cardiothorac Surg. 2012 Jul;42(1):e13-5; discusson e16. doi: 10.1093/ejcts/ezs195. Epub 2012 May 18.
Over the past 10 years, minimally invasive mitral valve surgery (MI-MVS) has become the standard approach for treatment of atrio-ventricular valve disease in specialized centres. This approach uses a right lateral mini-thoracotomy and femoral cannulation for cardiopulmonary bypass. In a very low number of patients, conversion to full sternotomy may be necessary.
A total of 3125 patients underwent MI-MVS between 1999 and 2010 at our institution. Conversion to full sternotomy was required in 1.0% (n=34) of all patients. Patient data, including intraoperative course and postoperative outcome, were collected. Follow-up data were collected in a prospective database and analysed retrospectively.
A total of 34 patients underwent conversion to full sternotomy during MI-MVS. The mean age of patients was 67.9±9.5 years, and 17 patients were female (50%). The main reasons for conversion were as follows: major bleeding in 18 patients (52.9%); severe pulmonary adhesions in six patients (17.6%); and aortic dissection in five patients (14.7%). The clinical outcome of these patients was impaired, with the development of acute renal failure in 13 patients (38.2%) and respiratory failure in 10 patients (29.4%). Operative mortality (30 days) was 23.5% (eight patients). The reason for death in all these patients was low cardiac output syndrome with subsequent multi-organ failure.
This large series shows that MI-MVS can be performed with very low complication rates. In the experience of this large single-centre study, conversion to full sternotomy was necessary in only 1% of all patients. If conversion is indicated, however, it is associated with a high operative mortality.
在过去的 10 年中,微创二尖瓣手术(MI-MVS)已成为专科中心治疗房室瓣疾病的标准方法。该方法采用右侧小开胸和股动脉插管进行体外循环。在极少数患者中,可能需要转换为全胸骨切开术。
1999 年至 2010 年,我们机构共对 3125 例患者进行了 MI-MVS。所有患者中有 1.0%(n=34)需要转换为全胸骨切开术。收集患者数据,包括术中过程和术后结果。前瞻性数据库收集随访数据并进行回顾性分析。
共有 34 例患者在 MI-MVS 期间转为全胸骨切开术。患者的平均年龄为 67.9±9.5 岁,其中 17 例为女性(50%)。转为全胸骨切开术的主要原因如下:18 例(52.9%)患者大出血;6 例(17.6%)患者严重肺粘连;5 例(14.7%)患者主动脉夹层。这些患者的临床结果受损,13 例(38.2%)患者发生急性肾功能衰竭,10 例(29.4%)患者发生呼吸衰竭。30 天内手术死亡率为 23.5%(8 例)。所有这些患者死亡的原因是低心输出量综合征伴随后多器官衰竭。
本大型系列研究表明,MI-MVS 可在并发症发生率极低的情况下进行。在这项大型单中心研究中,仅 1%的患者需要转换为全胸骨切开术。但是,如果需要转换,手术死亡率较高。