Gollmann-Tepeköylü Can, Nägele Felix, Höfer Daniel, Holfeld Johannes, Hirsch Jakob, Oezpeker Cenk Ulvi, Ruttmann-Ulmer Elfriede, Kilo Juliane, Hangler Herbert, Müller Ludwig, Grimm Michael, Bonaros Nikolaos
Department of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Interdiscip Cardiovasc Thorac Surg. 2023 Mar 2;36(3). doi: 10.1093/icvts/ivad030.
Minimally invasive mitral valve surgery (MIMVS) has evolved over the last 2 decades. The aim of the study was to identify the impact of era and technical improvements on perioperative outcome after MIMVS.
A tota of 1000 patients (mean age: 60.8 ± 12.7 years, 60.3% male) underwent video-assisted or totally endoscopic MIMVS between 2001 and 2020 in a single institution. Three technical modalities were introduced during the observed period: (i) 3D visualization, (ii) use of premeasured artificial chordae (PTFE loops) and (iii) preoperative CT scans. Comparisons were made before and after the introduction of technical improvements.
A total of 741 patients underwent isolated mitral valve (MV) procedure, whereas 259 received concomitant procedures. These consisted of tricuspid valve repair (208), left atrium ablation (145) and persistent foramen ovale or atrial septum defect (ASD) closure (172). The aetiology was degenerative in 738 (73.8%) patients and functional in 101 patients (10.1%). A total of 900 patients received MV repair (90%), and 100 patients (10%) underwent MV replacement. Perioperative survival was 99.1%, and periprocedural success 93.5% with a periprocedural safety of 96.3%. Improvement in periprocedural safety attributed to the lower rates of postoperative low output (P = 0.025) and less reoperations for bleeding (P < 0.001). 3D visualization improved cross-clamp (P = 0.001) but not cardiopulmonary bypass times. The use of loops and preoperative CT scan both had no impact on periprocedural success or safety but improved cardiopulmonary bypass and cross-clamp times (both P < 0.001).
Increased surgical experience improves safety in MIMVS. Technical improvements are related to increased operative success and decreased operative times in patients undergoing MIMVS.
微创二尖瓣手术(MIMVS)在过去20年中不断发展。本研究的目的是确定时代和技术改进对MIMVS术后围手术期结果的影响。
2001年至2020年期间,在单一机构中,共有1000例患者(平均年龄:60.8±12.7岁,男性占60.3%)接受了视频辅助或完全内镜下的MIMVS。在观察期间引入了三种技术模式:(i)3D可视化,(ii)使用预测量的人工腱索(PTFE环),以及(iii)术前CT扫描。在引入技术改进前后进行了比较。
共有741例患者接受了单纯二尖瓣(MV)手术,而259例接受了同期手术。这些同期手术包括三尖瓣修复(208例)、左心房消融(145例)和持续性卵圆孔未闭或房间隔缺损(ASD)封堵(172例)。病因在738例(73.8%)患者中为退行性,在101例患者(10.1%)中为功能性。共有900例患者接受了MV修复(90%),100例患者(10%)接受了MV置换。围手术期生存率为99.1%,手术成功率为93.5%,手术安全性为96.3%。围手术期安全性的提高归因于术后低心排血量发生率较低(P = 0.025)和因出血进行的再次手术较少(P < 0.001)。3D可视化改善了阻断时间(P = 0.001),但未改善体外循环时间。使用环和术前CT扫描对手术成功率或安全性均无影响,但改善了体外循环和阻断时间(均P < 0.001)。
手术经验的增加提高了MIMVS的安全性。技术改进与接受MIMVS患者的手术成功率提高和手术时间缩短有关。