Brooks A M, Grant G B, Gillies W E
Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.
Aust N Z J Ophthalmol. 1990 Aug;18(3):335-41. doi: 10.1111/j.1442-9071.1990.tb00630.x.
Corneal oedema and bullous keratopathy may occur following intraocular surgery or arise spontaneously in nonguttate eyes. In some patients the fellow eye shows a relatively normal endothelial cell count with abnormal pleomorphism and polymegathism of the endothelial cells, while in others it shows a markedly lowered endothelial cell count with no evidence of corneal guttae. A survey of 17 such patients suggested the following classification. 1. Nonguttate corneal endothelial dystrophy with irregular endothelial cell morphology but a relatively normal endothelial cell count occurring following surgery (eight patients) or spontaneously (four patients). 2. Nonguttate corneal endothelial dystrophy with grossly reduced endothelial cell count occurring spontaneously (two patients). Three additional post-surgical patients showed a relatively normal endothelial cell count and only mild changes in the morphology of the corneal endothelium. These findings support the presence of a nonguttate corneal endothelial dystrophy in both the spontaneous and some of the post-surgical cases.
角膜水肿和大疱性角膜病变可发生于眼内手术后，或在无角膜小滴的眼中自发出现。在一些患者中，对侧眼显示内皮细胞计数相对正常，但内皮细胞存在异常的多形性和大小不均，而在另一些患者中，对侧眼显示内皮细胞计数显著降低且无角膜小滴证据。对17例此类患者的调查提出了以下分类。1. 无角膜小滴的角膜内皮营养不良，内皮细胞形态不规则但内皮细胞计数相对正常，发生于手术后（8例患者）或自发出现（4例患者）。2. 无角膜小滴的角膜内皮营养不良，内皮细胞计数显著减少，自发出现（2例患者）。另外3例手术后患者显示内皮细胞计数相对正常，角膜内皮形态仅轻度改变。这些发现支持在自发和部分手术后病例中存在无角膜小滴的角膜内皮营养不良。
