Bates A K, Cheng H
Eye Hospital, Oxford.
Br J Ophthalmol. 1988 Jun;72(6):409-12. doi: 10.1136/bjo.72.6.409.
Preoperative and postoperative endothelial cell morphology was examined in three types of patients participating in a randomised, controlled trial of cataract surgery. The first sustained modest endothelial cell loss and served as controls, the second and third sustained high cell loss, but only the latter progressed to bullous keratopathy. The technique of examining endothelial cell morphology is described and its validity assessed. Measures of cell area, number of sides, side length, and variation in cell size and cell shape were utilised. No significant differences were found between the three groups by any of the preoperative morphological measures. Furthermore, postoperative values of variation in cell shape and cell size did not differ significantly between the groups. No evidence was found in our patients to support the hypothesis that eyes at particular risk of developing bullous keratopathy may be differentiated on the basis of their preoperative or early postoperative endothelial cell morphology.
在一项白内障手术随机对照试验的三类患者中，对术前和术后的内皮细胞形态进行了检查。第一类患者内皮细胞有适度损失，作为对照组，第二类和第三类患者内皮细胞损失严重，但只有后者发展为大泡性角膜病变。文中描述了检查内皮细胞形态的技术并评估了其有效性。采用了细胞面积、边数、边长以及细胞大小和形状变化的测量方法。术前的任何形态学测量指标在三组之间均未发现显著差异。此外，各组之间细胞形状和细胞大小变化的术后值也无显著差异。在我们的患者中，没有证据支持这样的假设，即根据术前或术后早期的内皮细胞形态可以区分出发生大泡性角膜病变风险特别高的眼睛。
