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卵巢双侧支持-间质细胞瘤:青少年男性化的罕见病因。

Bilateral androblastoma (Sertoli-stromal cell tumor) of the ovary: a rare cause of virilization in a teenager.

作者信息

Warenik-Szymankiewicz A, Słopień R, Gaca M, Kedzia H, Kadziołka P, Opala T

机构信息

Department of Gynecological Endocrinology, University of Medical Sciences of Poznań, Poland.

出版信息

Eur J Gynaecol Oncol. 2012;33(2):217-8.

Abstract

A case of a 17-year-old patient diagnosed with bilateral androblastoma of the ovary is presented. The patient was admitted because of secondary amenorrhea, hirsutism and acne. After clinical, ultrasonographic and hormonal examinations an androgen-producing ovarian tumor was suspected and consequently laparotomy with right ovarian tumor excision and left ovary exploration was carried out. During surgery the right ovarian tumor was excised and exploration of the left ovary revealed an ovarian tumor with a diameter of 10 mm, which was then also excised. The pathologic diagnosis was a bilateral androblastoma of the ovary measuring 40 mm x 30 mm x 20 mm in the right ovary and 10 mm in diameter in the left ovary. We concluded that androblastomas, in spite of their low incidence, are a possibility that should always be considered in women of all ages presenting with signs of virilization.

摘要

本文报告一例17岁诊断为双侧卵巢睾丸母细胞瘤的患者。该患者因继发性闭经、多毛症和痤疮入院。经过临床、超声和激素检查后,怀疑为产生雄激素的卵巢肿瘤,因此进行了剖腹手术,切除右侧卵巢肿瘤并探查左侧卵巢。手术中切除了右侧卵巢肿瘤,探查左侧卵巢时发现一个直径为10毫米的卵巢肿瘤,随后也将其切除。病理诊断为双侧卵巢睾丸母细胞瘤,右侧卵巢大小为40毫米×30毫米×20毫米,左侧卵巢直径为10毫米。我们得出结论,尽管睾丸母细胞瘤发病率较低,但对于所有出现男性化体征的各年龄段女性,都应始终考虑到这种可能性。

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