Centre for Integrated Research (CIR), Area of Diagnostic Imaging, Università Campus Bio-Medico di Roma, via Alvaro del Portillo, Rome, Italy.
Neurosci Biobehav Rev. 2012 Sep;36(8):1839-47. doi: 10.1016/j.neubiorev.2012.05.003. Epub 2012 May 18.
Body image distortion is a key symptom of anorexia nervosa (AN). The majority of the neuroimaging studies on body image distortion in AN conceptualized it as an unidimensional symptom. However, behavioural research considers such symptom as a multidimensional construct. Our paper systematically reviews the functional magnetic resonance (fMRI) studies on body image distortion in AN and classifies them according to a speculative model of body image distortion, that consists of the three most widely accepted components in the behavioural research: perceptive, affective and cognitive. We found that: (1) the perceptive component is mainly related to alterations of the precuneus and the inferior parietal lobe; (2) the affective component is mainly related to alterations of the prefrontal cortex, the insula and the amygdala; (3) the cognitive component has been weakly explored. These evidences seem to confirm that specific neural alterations are related to the components of the body image distortion in AN. Further neuroimaging studies are needed to better understand the complexity of the body image distortion in AN.
身体意象扭曲是神经性厌食症 (AN) 的一个关键症状。大多数关于 AN 中身体意象扭曲的神经影像学研究将其概念化为一种单一维度的症状。然而，行为研究将这种症状视为一种多维度的结构。我们的论文系统地回顾了关于 AN 中身体意象扭曲的功能磁共振成像 (fMRI) 研究，并根据身体意象扭曲的推测模型对其进行了分类，该模型由行为研究中最广泛接受的三个组成部分组成：感知、情感和认知。我们发现：（1）感知成分主要与楔前叶和下顶叶的改变有关；（2）情感成分主要与前额叶皮层、脑岛和杏仁核的改变有关；（3）认知成分的研究还很薄弱。这些证据似乎证实了特定的神经改变与 AN 中身体意象扭曲的成分有关。需要进一步的神经影像学研究来更好地理解 AN 中身体意象扭曲的复杂性。
