糖尿病性多发性神经病中的联合神经传导指数
Combined nerve conduction index in diabetic polyneuropathy.
作者信息
Heise Carlos Otto, Machado Flavia Costa Nunes, Amorim Simone Consuelo de, Toledo Sonia Maria de
机构信息
Fleury Institute, São Paulo, SP, Brazil.
出版信息
Arq Neuropsiquiatr. 2012 May;70(5):330-4. doi: 10.1590/s0004-282x2012000500005.
UNLABELLED
Diabetic polyneuropathy can be confirmed by nerve conduction studies. The data can be analyzed in the form of a combined index instead of individual parameters.
METHODS
The combined index included five parameters of nerve conduction studies commonly used for evaluation of polyneuropathies. We evaluated sensitivity in 100 diabetic patients with suspected polyneuropathy, and specificity in 200 non-diabetic patients with suspected lumbosacral radiculopathy. All results were expressed in number of standard deviations (SD).
RESULTS
The sensitivity of the combined index was 81 or 74%, and specificity was 97 or 98%, using respectively -2.0 or -2.5 SD as cutoff. The range of sensitivity of the other parameters was 57-65% or 48-56%, and specificity range was 96-98% or 98-100%, using the same criteria.
DISCUSSION
The combined index had higher sensitivity and equivalent specificity compared to isolated parameters.
未标注
糖尿病性多发性神经病可通过神经传导研究来确诊。数据可以采用综合指数的形式进行分析，而非单个参数。
方法
综合指数包括常用于评估多发性神经病的神经传导研究的五个参数。我们评估了100例疑似多发性神经病的糖尿病患者的敏感性，以及200例疑似腰骶神经根病的非糖尿病患者的特异性。所有结果均以标准差（SD）的数量表示。
结果
以-2.0或-2.5标准差作为临界值时，综合指数的敏感性分别为81%或74%，特异性为97%或98%。使用相同标准时，其他参数的敏感性范围为57 - 65%或48 - 56%，特异性范围为96 - 98%或98 - 100%。
讨论
与单独参数相比，综合指数具有更高的敏感性和相当的特异性。
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