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脑卒中后空间忽视认知不能的神经基础。

The neural basis of anosognosia for spatial neglect after stroke.

机构信息

Cognitive Neuroscience, Institute of Neuroscience and Medicine (INM-3), Research Centre Jülich, Leo-Brandt-Str 5, 52425 Jülich, Germany.

出版信息

Stroke. 2012 Jul;43(7):1954-6. doi: 10.1161/STROKEAHA.112.657288. Epub 2012 May 24.

DOI:10.1161/STROKEAHA.112.657288
PMID:22627992
Abstract

BACKGROUND AND PURPOSE

The present study investigated the lesion anatomy of anosognosia for visuospatial neglect resulting from right hemispheric stroke.

METHODS

In 63 patients, self-ratings of performance in paper-and-pencil tests were contrasted with external performance ratings. Lesion analysis was conducted on patient subgroups with different degrees of anosognosia but comparable visuospatial impairment.

RESULTS

Independent of the severity of visuospatial neglect per se, damage to the right angular and superior temporal gyrus was associated with higher levels of anosognosia.

CONCLUSIONS

Using a novel assessment of anosognosia for spatial neglect, the present study relates stroke-induced self-awareness deficits to inferior parietal and superior temporal brain damage.

摘要

背景与目的

本研究旨在探讨右半球卒中所致视空间忽略症的病变解剖学。

方法

在 63 名患者中,我们对比了他们在纸笔测试中的自我表现评分与外部表现评分。我们对具有不同程度但具有可比性的视空间缺损的患者亚组进行了病变分析。

结果

无论视空间忽略症的严重程度如何,右侧角回和颞上回的损伤与更高水平的认知失认症相关。

结论

本研究使用一种新颖的空间忽略认知失认症评估方法,将卒中引起的自我意识缺陷与顶下小叶和颞上叶的脑损伤联系起来。

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