• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
C. elegans feeding.秀丽隐杆线虫的进食
WormBook. 2012 May 21:1-23. doi: 10.1895/wormbook.1.150.1.
2
Serotonin activates overall feeding by activating two separate neural pathways in Caenorhabditis elegans.血清素通过激活秀丽隐杆线虫(Caenorhabditis elegans)中的两条独立神经通路来激活整体摄食。
J Neurosci. 2012 Feb 8;32(6):1920-31. doi: 10.1523/JNEUROSCI.2064-11.2012.
3
Pharyngeal timing and particle transport defects in feeding mutants.进食突变体的咽时间和颗粒输送缺陷。
J Neurophysiol. 2022 Aug 1;128(2):302-309. doi: 10.1152/jn.00444.2021. Epub 2022 Jun 22.
4
Pharyngeal pumping in Caenorhabditis elegans depends on tonic and phasic signaling from the nervous system.秀丽隐杆线虫的咽部抽吸依赖于来自神经系统的紧张性和阶段性信号传导。
Sci Rep. 2016 Mar 15;6:22940. doi: 10.1038/srep22940.
5
The pharynx of the nematode C. elegans: A model system for the study of motor control.线虫秀丽隐杆线虫的咽部:用于运动控制研究的模型系统。
Worm. 2013 Jan 1;2(1):e21833. doi: 10.4161/worm.21833.
6
Pharyngeal pumping continues after laser killing of the pharyngeal nervous system of C. elegans.秀丽隐杆线虫咽部神经系统被激光杀死后,咽部抽吸仍会继续。
Neuron. 1989 Oct;3(4):473-85. doi: 10.1016/0896-6273(89)90206-7.
7
Evolution of pharyngeal behaviors and neuronal functions in free-living soil nematodes.自由生活土壤线虫咽部行为和神经元功能的进化
J Exp Biol. 2006 May;209(Pt 10):1859-73. doi: 10.1242/jeb.02165.
8
Food transport in the C. elegans pharynx.秀丽隐杆线虫咽部的食物运输
J Exp Biol. 2003 Jul;206(Pt 14):2441-57. doi: 10.1242/jeb.00433.
9
Motor neuron M3 controls pharyngeal muscle relaxation timing in Caenorhabditis elegans.运动神经元M3控制秀丽隐杆线虫咽部肌肉的松弛时间。
J Exp Biol. 1993 Feb;175:283-97. doi: 10.1242/jeb.175.1.283.
10
Slow Ca2+ dynamics in pharyngeal muscles in Caenorhabditis elegans during fast pumping.秀丽隐杆线虫快速泵吸过程中咽部肌肉中缓慢的钙离子动力学。
EMBO Rep. 2004 May;5(5):521-6. doi: 10.1038/sj.embor.7400142. Epub 2004 Apr 16.

引用本文的文献

1
Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans.线粒体去乙酰化酶sir-2.2和sir-2.3调控秀丽隐杆线虫的寿命。
Genetics. 2025 Sep 5. doi: 10.1093/genetics/iyaf185.
2
Drug screens using the nematode Caenorhabditis elegans.使用线虫秀丽隐杆线虫进行药物筛选。
Genetics. 2025 Sep 3;231(1). doi: 10.1093/genetics/iyaf141.
3
Amitriptyline increases food intake via prdx-2 without altering other physiological parameters in C. elegans under a modified bacterial diet.在改良细菌饮食条件下,阿米替林通过prdx-2增加线虫的食物摄入量,而不改变其他生理参数。
Sci Rep. 2025 Aug 11;15(1):29428. doi: 10.1038/s41598-025-14773-8.
4
Herbo-Mineral Medicine, Cardiogrit Gold, Exhibits Protective Effects in Model of Doxorubicin-Induced Cardiotoxicity.草药-矿物药Cardiogrit Gold在阿霉素诱导的心脏毒性模型中具有保护作用。
J Toxicol. 2025 Jul 28;2025:4609428. doi: 10.1155/jt/4609428. eCollection 2025.
5
APOE4-induced patterned behavioral decline and neurodegeneration requires endogenous tau in a model of Alzheimer's disease.在阿尔茨海默病模型中,APOE4诱导的典型行为衰退和神经退行性变需要内源性tau蛋白。
bioRxiv. 2025 May 15:2025.05.06.652574. doi: 10.1101/2025.05.06.652574.
6
A comparative analysis of distinct assays for the investigation of behavior during organophosphate exposure.用于研究有机磷酸酯暴露期间行为的不同检测方法的比较分析。
MicroPubl Biol. 2025 May 16;2025. doi: 10.17912/micropub.biology.001533. eCollection 2025.
7
An enteric neuron-expressed variant ionotropic receptor detects ingested salts to regulate salt stress resistance.一种肠神经元表达的变异离子型受体检测摄入的盐分以调节耐盐胁迫能力。
bioRxiv. 2025 May 8:2025.04.11.648259. doi: 10.1101/2025.04.11.648259.
8
Satiety differentially modulates feeding steps in the jellyfish .饱腹感对水母的进食步骤有不同的调节作用。
iScience. 2025 Mar 10;28(4):112192. doi: 10.1016/j.isci.2025.112192. eCollection 2025 Apr 18.
9
Tolerance to a Diet of Toxic in .对……中毒性饮食的耐受性
Toxins (Basel). 2025 Feb 27;17(3):109. doi: 10.3390/toxins17030109.
10
Pharyngeal Pumping Assay for Quantifying Feeding Behavior in .用于量化……摄食行为的咽泵试验
Bio Protoc. 2024 Sep 20;14(18):e5073. doi: 10.21769/BioProtoc.5073.

秀丽隐杆线虫的进食

C. elegans feeding.

作者信息

Avery Leon, You Young-Jai

机构信息

Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA, USA.

出版信息

WormBook. 2012 May 21:1-23. doi: 10.1895/wormbook.1.150.1.

DOI:10.1895/wormbook.1.150.1
PMID:22628186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3590810/
Abstract

C. elegans feeding depends on the action of the pharynx, a neuromuscular pump that joins the mouth to the intestine. The pharyngeal muscle captures food-bacteria-and transports it back to the intestine. It accomplishes this through a combination of two motions, pumping and isthmus peristalsis. Pumping, the most visible and best understood of the two, is a cycle of contraction and relaxation that sucks in liquid from the surrounding environment along with suspended particles, then expels the liquid, trapping the particles. Pharyngeal muscle is capable of pumping without nervous system input, but during normal rapid feeding its timing is controlled by two pharyngeal motor neuron types. Isthmus peristalsis, a posterior moving wave of contraction of the muscle of the posterior isthmus, depends on a third motor neuron type. Feeding motions are regulated by the presence and quality of food in the worm's environment. Some types of bacteria are better at supporting growth than others. Given a choice, worms are capable of identifying and seeking out higher-quality food. Food availability and quality also affect behavior in other ways. For instance, given all the high-quality food they can eat, worms eventually become satiated, stop eating and moving, and become quiescent.

摘要

秀丽隐杆线虫的进食依赖于咽部的活动,咽部是一个将口与肠道相连的神经肌肉泵。咽部肌肉捕获食物(细菌)并将其输送回肠道。它通过两种运动的组合来完成这一过程,即抽吸和峡部蠕动。抽吸是这两种运动中最明显且最易理解的,它是一个收缩和舒张的循环,从周围环境中吸入液体以及悬浮颗粒,然后排出液体,捕获颗粒。咽部肌肉在没有神经系统输入的情况下也能够进行抽吸,但在正常快速进食期间,其时间控制由两种类型的咽部运动神经元负责。峡部蠕动是峡部后部肌肉的一种向后移动的收缩波,它依赖于第三种运动神经元类型。进食动作受线虫所处环境中食物的存在和质量的调节。某些类型的细菌比其他细菌更有利于生长。在有选择的情况下,线虫能够识别并寻找更高质量的食物。食物的可获得性和质量也会以其他方式影响行为。例如,如果有足够的高质量食物可供食用,线虫最终会吃饱,停止进食和移动,并进入静止状态。