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秀丽隐杆线虫的进食

C. elegans feeding.

作者信息

Avery Leon, You Young-Jai

机构信息

Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA, USA.

出版信息

WormBook. 2012 May 21:1-23. doi: 10.1895/wormbook.1.150.1.

Abstract

C. elegans feeding depends on the action of the pharynx, a neuromuscular pump that joins the mouth to the intestine. The pharyngeal muscle captures food-bacteria-and transports it back to the intestine. It accomplishes this through a combination of two motions, pumping and isthmus peristalsis. Pumping, the most visible and best understood of the two, is a cycle of contraction and relaxation that sucks in liquid from the surrounding environment along with suspended particles, then expels the liquid, trapping the particles. Pharyngeal muscle is capable of pumping without nervous system input, but during normal rapid feeding its timing is controlled by two pharyngeal motor neuron types. Isthmus peristalsis, a posterior moving wave of contraction of the muscle of the posterior isthmus, depends on a third motor neuron type. Feeding motions are regulated by the presence and quality of food in the worm's environment. Some types of bacteria are better at supporting growth than others. Given a choice, worms are capable of identifying and seeking out higher-quality food. Food availability and quality also affect behavior in other ways. For instance, given all the high-quality food they can eat, worms eventually become satiated, stop eating and moving, and become quiescent.

摘要

秀丽隐杆线虫的进食依赖于咽部的活动,咽部是一个将口与肠道相连的神经肌肉泵。咽部肌肉捕获食物(细菌)并将其输送回肠道。它通过两种运动的组合来完成这一过程,即抽吸和峡部蠕动。抽吸是这两种运动中最明显且最易理解的,它是一个收缩和舒张的循环,从周围环境中吸入液体以及悬浮颗粒,然后排出液体,捕获颗粒。咽部肌肉在没有神经系统输入的情况下也能够进行抽吸,但在正常快速进食期间,其时间控制由两种类型的咽部运动神经元负责。峡部蠕动是峡部后部肌肉的一种向后移动的收缩波,它依赖于第三种运动神经元类型。进食动作受线虫所处环境中食物的存在和质量的调节。某些类型的细菌比其他细菌更有利于生长。在有选择的情况下,线虫能够识别并寻找更高质量的食物。食物的可获得性和质量也会以其他方式影响行为。例如,如果有足够的高质量食物可供食用,线虫最终会吃饱,停止进食和移动,并进入静止状态。

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