Lahmer Tobias, Küchle Claudius, Schirmer Lucas, Heemann Uwe, Lutz Jens, Thürmel Klaus
Department of Nephrology, Klinikum rechts der Isar, Technische Universitaet Muenchen, Germany.
Exp Clin Transplant. 2012 Jun;10(3):299-301. doi: 10.6002/ect.2011.0177.
Posterior reversible encephalopathy syndrome is characterized by varying neurologic symptoms associated with brain vasogenic edema. Posterior reversible encephalopathy syndrome can be associated with severe hypertension (eg, in eclampsia or HELLP syndrome), but it also has been observed without hypertension and in several clinical conditions including infections and autoimmune disorders. The literature offers several reports of posterior reversible encephalopathy syndrome detected or induced after bone-marrow and solid-organ transplant, or induction by immunosuppression. We describe what is, to the best of our knowledge, the first case of man who successfully underwent a kidney transplant with preexisting posterior reversible encephalopathy syndrome induced by Goodpasture's syndrome.
后部可逆性脑病综合征的特征是伴有脑血管源性水肿的各种神经系统症状。后部可逆性脑病综合征可与严重高血压相关（如子痫或 HELLP 综合征），但在无高血压的情况下以及在包括感染和自身免疫性疾病在内的多种临床情况下也有观察到。文献中有几篇关于在骨髓和实体器官移植后检测到或诱发后部可逆性脑病综合征，或由免疫抑制诱发该综合征的报道。据我们所知，我们描述了首例患有由 Goodpasture 综合征诱发的后部可逆性脑病综合征且成功接受肾移植的男性病例。
