Institute of Neuroradiology, Gutenberg University Medical Center, Langenbeckstreet 1, Mainz 55131, Germany.
Best Pract Res Clin Endocrinol Metab. 2012 Jun;26(3):259-71. doi: 10.1016/j.beem.2011.11.009.
Neuroimaging of Graves' orbitopathy (GO) plays an important role in the differential diagnosis and interdisciplinary management of patients with GO. Orbital imaging is required in unclear or asymmetric proptosis, in suspected optic neuropathy and prior to decompression surgery. Especially computed tomography and magnetic resonance (MR) imaging show the actual objective morphological findings, quantitative MR imaging giving additional information concerning the acuteness or chronicity of the disease. Major morphological diagnostic criteria include a spindle like spreading of the rectus muscles without involvement of the tendon, a compression of the optic nerve in the orbital apex (crowded orbital apex syndrome) and the absence of any space occupying intraorbital process. A longer lasting course of the disease may lead to a corresponding impression of the lamina papyracae, the normally parallel configured medial wall of the orbit, similar to a spontaneous decompression.
格雷夫斯眼病（GO）的神经影像学在 GO 患者的鉴别诊断和跨学科管理中起着重要作用。在眼球突出不明显或不对称、疑似视神经病变以及在减压手术之前，需要进行眼眶成像。特别是计算机断层扫描和磁共振成像（MR）显示了实际的客观形态学发现，定量 MR 成像提供了有关疾病的急性或慢性的额外信息。主要的形态学诊断标准包括直肌呈纺锤形扩张而肌腱不受累、眶尖视神经受压（拥挤眶尖综合征）以及没有任何占位性眶内病变。疾病持续时间较长可能导致纸样板相应的印象，即正常平行排列的眼眶内侧壁，类似于自发性减压。
