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视词汇区的解剖结构:毗邻的皮质回路和长程白质连接。

Anatomy of the visual word form area: adjacent cortical circuits and long-range white matter connections.

机构信息

Psychology Department, Stanford University, Stanford, CA 94305, United States.

出版信息

Brain Lang. 2013 May;125(2):146-55. doi: 10.1016/j.bandl.2012.04.010. Epub 2012 May 23.

Abstract

Circuitry in ventral occipital-temporal cortex is essential for seeing words. We analyze the circuitry within a specific ventral-occipital region, the visual word form area (VWFA). The VWFA is immediately adjacent to the retinotopically organized VO-1 and VO-2 visual field maps and lies medial and inferior to visual field maps within motion selective human cortex. Three distinct white matter fascicles pass within close proximity to the VWFA: (1) the inferior longitudinal fasciculus, (2) the inferior frontal occipital fasciculus, and (3) the vertical occipital fasciculus. The vertical occipital fasciculus terminates in or adjacent to the functionally defined VWFA voxels in every individual. The vertical occipital fasciculus projects dorsally to language and reading related cortex. The combination of functional responses from cortex and anatomical measures in the white matter provides an overview of how the written word is encoded and communicated along the ventral occipital-temporal circuitry for seeing words.

摘要

腹侧枕颞皮质中的回路对于看见单词至关重要。我们分析了特定的腹侧枕区,即视觉单词形式区(VWFA)的回路。VWFA 紧邻视知觉组织的 VO-1 和 VO-2 视野图,位于运动选择人类皮质内的视野图内侧和下方。三个不同的白质束纤维束在 VWFA 附近紧密接近:(1)下纵束,(2)下额枕束,和(3)垂直枕束。在每个人中,垂直枕束终止于或邻近于功能定义的 VWFA 体素。垂直枕束向语言和阅读相关的皮质投射。皮质的功能反应和白质中的解剖学测量相结合,提供了一个概述,说明书面单词如何沿着腹侧枕颞回路进行编码和交流,以实现看见单词的功能。

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本文引用的文献

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Compressive spatial summation in human visual cortex.人类视觉皮层中的压缩空间总和。
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Annu Rev Psychol. 2012;63:31-53. doi: 10.1146/annurev-psych-120710-100434. Epub 2011 Jul 29.
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