Kostić V, Covicković-Sternić N, Filipović S
Department of Neurology, University Clinical Center, Beograd.
Neurologija. 1990;39(1):29-33.
Fifteen patients with spasmodic torticollis were treated with local injections of botulinum--A toxin. All the patients were followed for a period of 4 to 7 months. Thirteen out of 15 patients (86%) improved in the amount of sustained movements of torticollis. In six out of 9 patients presenting with pain complete relief was noted. Beneficial effects of botulinum toxin injections lasted from 2 to 3 months, with reproducible efficacy after repeated injections. The most frequent side effect was dysphagia, presented in 10 patients.
15例痉挛性斜颈患者接受了肉毒杆菌A毒素局部注射治疗。所有患者均随访4至7个月。15例患者中有13例(86%)斜颈持续运动量有所改善。9例有疼痛症状的患者中,6例疼痛完全缓解。肉毒杆菌毒素注射的有益效果持续2至3个月,重复注射后疗效可再现。最常见的副作用是吞咽困难,10例患者出现该症状。