School of Psychological Sciences, University of Manchester, United Kingdom.
Brain Lang. 2012 Jul;122(1):42-54. doi: 10.1016/j.bandl.2012.04.014. Epub 2012 May 26.
The role of speech production mechanisms in difficult speech comprehension is the subject of on-going debate in speech science. Two Activation Likelihood Estimation (ALE) analyses were conducted on neuroimaging studies investigating difficult speech comprehension or speech production. Meta-analysis 1 included 10 studies contrasting comprehension of less intelligible/distorted speech with more intelligible speech. Meta-analysis 2 (21 studies) identified areas associated with speech production. The results indicate that difficult comprehension involves increased reliance of cortical regions in which comprehension and production overlapped (bilateral anterior Superior Temporal Sulcus (STS) and anterior Supplementary Motor Area (pre-SMA)) and in an area associated with intelligibility processing (left posterior MTG), and second involves increased reliance on cortical areas associated with general executive processes (bilateral anterior insulae). Comprehension of distorted speech may be supported by a hybrid neural mechanism combining increased involvement of areas associated with general executive processing and areas shared between comprehension and production.
言语产生机制在言语理解困难中的作用是言语科学中正在讨论的一个主题。对研究言语理解困难或言语产生的神经影像学研究进行了两次激活似然估计（ALE）分析。元分析 1 包括 10 项研究，比较了理解不太清晰/失真的言语与更清晰言语的情况。元分析 2（21 项研究）确定了与言语产生相关的区域。结果表明，理解困难涉及到对重叠的理解和产生区域（双侧前颞上回（STS）和前辅助运动区（pre-SMA））以及与可理解性处理相关的区域（左侧后颞上回（MTG））的依赖增加，其次涉及到对与一般执行过程相关的皮质区域的依赖增加（双侧前岛叶）。对失真言语的理解可能由一种混合神经机制支持，该机制结合了与一般执行处理相关的区域和理解与产生之间共享的区域的增加参与。
