Jain Nirdesh, Himanshu Dandu, Verma Shailendra Prasad, Parihar Anit
Department of Medicine, Chhatrapati Shahuji Maharaj Medical University, Lucknow, India.
Ann Saudi Med. 2013 Jan-Feb;33(1):68-9. doi: 10.5144/0256-4947.2012.26.5.1114.
Acute methanol intoxication is not an unusual poisoning. It can have serious neurological sequelae. We emphasize how neuroimaging can help in distinguishing methanol poisoning from other causes of acute unconsciousness in alcoholic patients such as hypoglycemic brain damage and carbon monoxide poisoning or head injury, which are frequently observed in alcoholic patients and are also responsible for altered sensorium. The most important findings in MR brain imaging in methanol poisoning have been bilateral putaminal hemorrhagic necrosis. Other less common findings are subcortical and deep white matter lesions, cerebral and cerebellar cortical lesions, and midbrain lesions, cerebral and intraventricular hemorrhage, and even enhancement of necrotic lesions, we found almost the entire spectrum of MRI findings in this patient with methanol poisoning. Neurological sequelae can entail the course and prognosis in methanol poisoning. The patient died because of ventilator-associated pneumonia that developed in the course of prolonged hospitalization.
急性甲醇中毒并非罕见的中毒情况。它可导致严重的神经后遗症。我们强调神经影像学如何有助于鉴别甲醇中毒与酒精性患者急性意识丧失的其他原因，如低血糖脑损伤、一氧化碳中毒或头部损伤，这些情况在酒精性患者中经常出现，也可导致意识改变。甲醇中毒患者脑部磁共振成像的最重要表现是双侧壳核出血性坏死。其他较不常见的表现包括皮质下和深部白质病变、大脑和小脑皮质病变、中脑病变、脑内和脑室内出血，甚至坏死性病变强化，我们在该甲醇中毒患者中发现了几乎所有磁共振成像表现。神经后遗症可影响甲醇中毒的病程和预后。患者因长期住院期间发生的呼吸机相关性肺炎而死亡。
