Hoang Thao Nguyen, Bich Van Le Thi, Thien Tuong Cao, The Hiep Truong, Tri Dung Pham, Van Phuoc Le
Department of Radiology, Cho Ray Hospital, Ho Chi Minh, Vietnam.
Emergency Department, Cho Ray Hospital, Ho Chi Minh, Vietnam.
Radiol Case Rep. 2023 Oct 6;18(12):4414-4418. doi: 10.1016/j.radcr.2023.09.019. eCollection 2023 Dec.
Acute methanol intoxication is uncommon. Methanol is mildly toxic, but its metabolites are formic acid and formaldehyde, causing total metabolism, visual disturbances, and central nervous system disturbances, leading to coma and death. Magnetic resonance imaging (MRI) is very important for the diagnosis and prognosis of methanol intoxication. Putaminal necrosis with or without hemorrhage is the most frequently reported finding. Other affected areas that are reported in the literature are subcortical white matter, hippocampus, optic nerve, and cerebellum. We report 3 cases of methanol intoxication and discuss their brain lesions on MRI.
急性甲醇中毒并不常见。甲醇毒性轻微，但其代谢产物为甲酸和甲醛，可导致全身代谢紊乱、视觉障碍及中枢神经系统紊乱，进而引发昏迷和死亡。磁共振成像（MRI）对于甲醇中毒的诊断及预后评估非常重要。壳核坏死伴或不伴出血是最常报道的发现。文献中报道的其他受累区域包括皮质下白质、海马、视神经及小脑。我们报告3例甲醇中毒病例，并讨论其MRI上的脑部病变。
