Bousquet François, Ferveur Jean-François
Centre des Sciences du Goût et de l'Alimentation, UMR CNRS, UMR INRA, Université de Bourgogne, Dijon, France.
Fly (Austin). 2012 Apr-Jun;6(2):102-7. doi: 10.4161/fly.19554. Epub 2012 Apr 1.
The desat1 gene possesses an extraordinary-maybe unique-feature in the control of sensory communication systems: it codes for the two principal and complementary aspects-the emission and the reception-of Drosophila sex pheromones. These two complex aspects depend on separate genetic control indicating that desat1 pleiotropically acts on pheromonal communication. This gene also control other characters either related to reproduction and to osmoregulation. Such a functional pleiotropy may be related to the molecular structure of desat1 gene which combines a highly conserved coding region with fast evolving regulatory regions: It produces at least five transcripts all giving rise to the ∆9-desaturase enzyme.
desat1基因在感觉通讯系统的控制方面具有一个非同寻常的——也许是独一无二的——特征：它编码果蝇性信息素的两个主要且互补的方面——释放和接收。这两个复杂的方面依赖于独立的遗传控制，表明desat1对信息素通讯具有多效性作用。该基因还控制其他与生殖和渗透调节相关的性状。这种功能多效性可能与desat1基因的分子结构有关，该结构将高度保守的编码区域与快速进化的调控区域结合在一起：它至少产生五种转录本，所有转录本都能产生∆9-去饱和酶。
