Carpenter Ashley R, Becknell Brian, Ingraham Susan E, McHugh Kirk M
Center for Molecular and Human Genetics, Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Methods Mol Biol. 2012;886:403-10. doi: 10.1007/978-1-61779-851-1_35.
Ultrasound (US) is the most common and least invasive modality for clinical imaging of the kidney. One important application of US in nephrology is the detection and monitoring of structural changes in the kidney. Recent advances in US technology have facilitated the application of similar techniques to animal models of human disease. We have developed a simple US-based method of detection and quantitation of hydronephrosis in a mouse model of congenital obstructive nephropathy, the megabladder (mgb) mouse.
超声（US）是肾脏临床成像中最常用且侵入性最小的检查方式。超声在肾脏病学中的一个重要应用是检测和监测肾脏结构变化。超声技术的最新进展推动了类似技术在人类疾病动物模型中的应用。我们已经开发出一种基于超声的简单方法，用于在先天性梗阻性肾病的小鼠模型——巨膀胱（mgb）小鼠中检测和定量肾盂积水。
