Hampson Christopher O, Soares Gregory M, Jaffan Abdel Aziz
Department of Diagnostic Imaging, Warren Alpert School of Medicine at Brown University, Rhode Island Hospital, Providence, RI 02903, USA.
Tech Vasc Interv Radiol. 2012 Jun;15(2):144-9. doi: 10.1053/j.tvir.2012.02.007.
Chronic cerebrospinal venous insufficiency (CCSVI) has recently been implicated as a potential causal factor in the development of multiple sclerosis (MS). The treatment of jugular and azygous vein stenoses, characteristic of CCSVI, has been proposed as a potential component of therapy for MS. In the few short years since Dr. Paulo Zamboni published "A Prospective Open label Study of Endovascular Treatment of Chronic Cerebrospinal Venous Insufficiency", there has been tremendous patient-driven demand for treatment. Concurrently, there have been numerous publications since 2009 addressing CCSVI and its association with MS. The purpose of this article is to present a brief review of CCSVI and its association with MS and to review the available literature to date with a focus on outcomes data.
慢性脑脊髓静脉功能不全（CCSVI）最近被认为是多发性硬化症（MS）发病的一个潜在致病因素。CCSVI所特有的颈静脉和奇静脉狭窄的治疗方法，已被提议作为MS治疗的一个潜在组成部分。自保罗·赞博尼博士发表《慢性脑脊髓静脉功能不全血管内治疗的前瞻性开放标签研究》以来的短短几年里，患者对治疗的需求巨大。同时，自2009年以来，有大量关于CCSVI及其与MS关联的出版物。本文的目的是简要回顾CCSVI及其与MS的关联，并回顾迄今为止的现有文献，重点关注疗效数据。
