Schuierer G, Huk W J
Department of Neuroradiology, University Erlangen-Nuremberg, F.R.G.
Stroke. 1990 Dec;21(12):1674-9. doi: 10.1161/01.str.21.12.1674.
The presence of an area of reversed blood flow due to flow separation in the interval carotid artery is a normal finding in Doppler ultrasound studies in vivo as well as in model carotid bifurcations. This flow separation phenomenon is caused by the geometry of the carotid bifurcation and the fluid dynamics of blood. We demonstrated the flow separation phenomenon on lateral-projection intra-arterial digital subtraction angiograms in 99 of 100 carotid bifurcations. The mean duration of flow separation was 5.8 seconds, with values up to 14 seconds in normal carotid bifurcations. The presence of this flow separation phenomenon is almost independent of atherosclerotic lesions and is not correlated with cerebral ischemia. Therefore, the angiographic finding of a flow separation has no diagnostic value. However, our results refer to a factor that may be important in the genesis of atherosclerosis at the carotid bifurcation, namely the duration of the stay of blood and its components within the area of flow separation.
在体内的多普勒超声研究以及模型颈动脉分叉中，由于颈内动脉节段内血流分离导致的反向血流区域的存在是一种正常发现。这种血流分离现象是由颈动脉分叉的几何形状和血液的流体动力学引起的。我们在100个颈动脉分叉中的99个的侧位动脉内数字减影血管造影上证实了血流分离现象。血流分离的平均持续时间为5.8秒，正常颈动脉分叉中值可达14秒。这种血流分离现象的存在几乎与动脉粥样硬化病变无关，且与脑缺血无关。因此，血流分离的血管造影表现没有诊断价值。然而，我们的结果涉及一个可能在颈动脉分叉处动脉粥样硬化发生中起重要作用的因素，即血液及其成分在血流分离区域内停留的持续时间。
