Modvig Signe, Høi-Hansen Christina Engel, Uldall Peter, Somnier Finn
Neurologisk Afdeling, Glostrup Hospital, Nordre Ringvej 57, Glostrup.
Ugeskr Laeger. 2012 May 21;174(21):1456-8.
Autoimmune synaptic encephalitis (ASE) is a recently recognized disease entity. The early and correct diagnosis of ASE is of importance, since the prognosis depends on the early onset of treatment. We present two Danish case reports of ASE: a 15-year-old boy presenting with a severe course of N-methyl-D-aspartate-encephalitis including persistent cognitive deficits, and a 59-year-old woman with coeliac disease presenting with leucine-rich glioma inactivated 1-encephalitis including dyskinesia, epilepsy, psychiatric features and vocal tics.
自身免疫性突触性脑炎(ASE)是一种最近才被认识的疾病实体。ASE的早期正确诊断至关重要,因为预后取决于治疗的早期开始。我们报告两例丹麦的ASE病例:一名15岁男孩,患有严重的N-甲基-D-天冬氨酸受体脑炎,包括持续的认知缺陷;一名59岁患有乳糜泻的女性,患有富含亮氨酸的胶质瘤失活1型脑炎,包括运动障碍、癫痫、精神症状和发声抽动。