Department of Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.
Int J Psychiatry Med. 2012;43(1):51-65. doi: 10.2190/PM.43.1.d.
Psychiatric conditions are known to have a detrimental impact on functioning and may therefore influence patterns of disability associated with MS. Population-based studies are needed to evaluate such interactions. The objective of this study was to describe the pattern of interaction of MS and mental disorders on health-related impairments.
The Participation and Activity Limitation Survey (PALS) was a post-censual survey conducted by Statistics Canada in association with the 2006 Canadian Census. PALS collected detailed data from a random sample of n = 28,640 respondents with health-related impairments reported on their census form. The PALS interview collected self-reported diagnostic data and included scales to assess functioning and participation in society.
PALS identified 245 individuals with MS, leading to an estimated (weighted) population prevalence of 0.2% (200 per 100,000), consistent with other Canadian estimates. As expected, impaired agility, vision, communication, mobility, pain, and memory were strongly associated with MS. Mental disorders were also associated with impairment, but interactions between these conditions and MS were generally not evident.
Mental disorders are associated with a higher level of disability in MS but, with the exception of communication, there was no evidence of synergistic interaction between mental disorders and MS in contributing to health-related impairments.
已知精神疾病对功能有不利影响,因此可能影响与 MS 相关的残疾模式。需要进行基于人群的研究来评估这种相互作用。本研究的目的是描述 MS 和精神障碍对健康相关障碍的相互作用模式。
参与和活动障碍调查(PALS)是加拿大统计局与 2006 年加拿大人口普查相关联进行的一项事后调查。PALS 从在其人口普查表上报告健康相关障碍的 n = 28,640 名随机样本中收集了详细数据。PALS 访谈收集了自我报告的诊断数据,并包括评估功能和参与社会的量表。
PALS 确定了 245 名 MS 患者,估计(加权)人群患病率为 0.2%(每 100,000 人中有 200 人),与其他加拿大估计值一致。如预期的那样,运动敏捷性、视力、沟通、移动性、疼痛和记忆力受损与 MS 密切相关。精神障碍也与障碍有关,但这些疾病与 MS 之间的相互作用通常不明显。
精神障碍与 MS 患者的残疾程度更高相关,但除了沟通障碍外,精神障碍和 MS 之间没有协同作用导致健康相关障碍。