Jones T O, Clegg F G, Morgan G, Wijeratne W V
Ministry of Agriculture, Fisheries and Food Veterinary Investigation Centre, Sutton Bonington, Loughborough.
Vet Rec. 1990 Oct 27;127(17):421-4.
A new form of bilateral renal dysplasia in lambs appeared in a commercial sheep flock in 1982. The nature of the problem, the field investigations and the laboratory examinations carried out over three lambing seasons are described. It was concluded that the condition was vertically transmitted and genetic in origin. During the two years that accurate records were kept approximately 30 per cent of the suspected ram's progeny died with lesions of renal dysplasia. The condition recurred during a breeding trial in progeny from one of the two commercial rams originally used on the farm. An autosomal dominant mode of inheritance is suggested. The incidence illustrates the importance of keeping breeding records, especially when several rams are maintained in a flock, and the value of examining a large number of lambs post mortem.
1982年，一种新形式的羔羊双侧肾发育异常出现在一个商业羊群中。本文描述了该问题的性质、在三个产羔季节进行的现场调查和实验室检查。得出的结论是，该病是垂直传播的，起源于遗传。在保存准确记录的两年中，大约30%疑似公羊的后代死于肾发育异常病变。在对最初用于该农场的两只商业公羊之一的后代进行的育种试验中，该病再次出现。提示为常染色体显性遗传模式。发病率说明了保存育种记录的重要性，特别是当一个羊群中饲养几只公羊时，以及对大量羔羊进行死后检查的价值。
